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. 2021 May 26;4(3):130-135.
doi: 10.1016/j.jimed.2021.05.006. eCollection 2021 Aug.

Endovascular denervation (EDN): From Hypertension to Non-Hypertension Diseases

Tao Pan  1 , Qi Zhang  1 , Jinhe Guo  1
Affiliations

Endovascular denervation (EDN): From Hypertension to Non-Hypertension Diseases

Tao Pan et al. J Interv Med. .

Abstract

Recently, the use of endovascular denervation (EDN) to treat resistant hypertension has gained significant attention. In addition to reducing sympathetic activity, EDN might also have beneficial effects on pulmonary arterial hypertension, insulin resistance, chronic kidney disease, atrial fibrillation, heart failure, obstructive sleep apnea syndrome, loin pain hematuria syndrome, cancer pain and so on. In this article we will summarize the progress of EDN in clinical research.

Keywords: Clinical research; Endovascular denervation; Resistant hypertension; Sympathetic activity.

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Conflict of interest statement

All the authors disclose none actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work.

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References

    1. Cannon W.B. Chemical mediators OF autonomic nerve impulses. Science. 1933;78:43–48. - PubMed
    1. Böhm M., Linz D., Urban D. Renal sympathetic denervation: applications in hypertension and beyond. Nat Rev Cardiol. 2013;10:465–476. - PubMed
    1. Esler M. The 2009 Carl Ludwig Lecture: pathophysiology of the human sympathetic nervous system in cardiovascular diseases: the transition from mechanisms to medical management. J Appl Physiol (1985) 2010;108:227–237. - PubMed
    1. Ahmari N., Hayward L.F., Zubcevic J. The importance of bone marrow and the immune system in driving increases in blood pressure and sympathetic nerve activity in hypertension. Exp Physiol. 2020;105:1815–1826. - PubMed
    1. Carnagarin R., Matthews V.B., Herat L.Y. Autonomic regulation of glucose homeostasis: a specific role for sympathetic nervous system Activation. Curr Diabetes Rep. 2018;18:107. - PubMed

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