Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2022 Feb;40(2):483-487.
doi: 10.1007/s00345-021-03882-4. Epub 2021 Nov 22.

Synchronous transurethral cystolitholapaxy and TURP reveals better results than transurethral cystolitholapaxy plus medical therapy for BPH: a randomized prospective study on 100 patients with concomitant urinary bladder stone(s) and BPH

Ahmed Mahmoud Hasan  1 , Mostafa AbdelRazek  2 , Atef Fathi Ali  2 , Omar Mohamed Alsaghier  2 , Ahmed Abdein Ahmed  2 , Gamal Abdelhamid Alsaghier  2
Affiliations
Randomized Controlled Trial

Synchronous transurethral cystolitholapaxy and TURP reveals better results than transurethral cystolitholapaxy plus medical therapy for BPH: a randomized prospective study on 100 patients with concomitant urinary bladder stone(s) and BPH

Ahmed Mahmoud Hasan et al. World J Urol. 2022 Feb.

Abstract

Objective: This report presents the results of a randomized prospective study comparing synchronous transurethral cystolitholapaxy and transurethral resection of the prostate (TURP) with transurethral cystolitholapaxy plus medical treatment for benign prostatic hyperplasia (BPH) in patients with concomitant vesical stone(s) and BPH.

Patients and methods: The study included 100 patients with bladder stone(s) < 2.5 cm associated with BPH. Eligible patients were divided randomly into two groups: group I (n = 50 patients) underwent simultaneous transurethral cystolitholapaxy and TURP, and group II (n = 50 patients) underwent transurethral cystolitholapaxy and received postoperative tamsulosin plus finasteride.

Results: The mean follow-up was 20.1 ± 5.3 months. No statistically significant differences were found between the 2 groups regarding the preoperative parameters (age, prostatic volume, bladder stone characteristics, prostate-specific antigen level, International Prostate Symptom Score, peak urinary flow rate, and post-void residual urine volume). Both groups experienced statistically significant postoperative improvement in IPSS, post-void residual (PVR) urine volume, and peak flow rate compared with the preoperative parameters (P < 0.001 for all parameters). However, patients in group 1 had a more pronounced improvement (P < 0.001 for all parameters). Thus, 15 patients in group 2 underwent TURP during follow-up. PVR urine and prostate volume predicted the failure of medical therapy and the need for TURP.

Conclusion: Synchronous transurethral cystolitholapaxy and TURP revealed better results than transurethral cytolitholapaxy plus medical therapy. Cystolitholapaxy without TURP should not be indicated especially in patients with significant PVR urine volumes and larger prostates.

Keywords: BPH; Litholapaxy; TURP; Vesical stones.

PubMed Disclaimer

References

    1. Lee SWH, Chan EMC, Lai YK (2017) The global burden of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a systematic review and meta-analysis. Sci Rep 7(1):1–10 - DOI
    1. Abrams P, Chapple C, Khoury S, Roehrborn C, de la Rosette J (2009) International Scientific Committee. Evaluation and treatment of lower urinary tract symptoms in older men. J Urol 181:1779–1787 - DOI
    1. Oelke M, Bachmann A, Descazeaud A et al (2013) Guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol 64:118–140 - DOI
    1. Jiwrajka M, Yaxley W, Perera M et al (2018) Review and update of benign prostatic hyperplasia in general practice. Aust J Gen Pract 47:471–475 - DOI
    1. Metwally AH, Sherief MH, Elkoushy MA (2016) Safety and efficacy of cystoscopically guided percutaneous suprapubic cystolitholapaxy without fluoroscopic guidance. Arab J Urol 14(3):211–215 - DOI

Publication types

LinkOut - more resources