Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan-Feb;97(1):127-128.
doi: 10.1016/j.abd.2021.05.010. Epub 2021 Nov 19.

Vandetanib induced phototoxic reaction progressed to toxic epidermal necrolysis

Busra Demirbag Gul  1 , Nilgun Senturk  2 , Deniz Baycelebi  3 , Levent Yildiz  3
Affiliations

Vandetanib induced phototoxic reaction progressed to toxic epidermal necrolysis

Busra Demirbag Gul et al. An Bras Dermatol. 2022 Jan-Feb.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Diffuse epidermal detachment was seen on face.
Figure 2
Figure 2
Diffuse epidermal detachment was seen on arms.
Figure 3
Figure 3
Basal cell vacuolation and subepidermal clivage was seen in light microscopy (Hematoxylin & eosin, ×100).
See this image and copyright information in PMC

References

    1. Vozniak J.M., Jacobs J.M. Vandetanib. J Adv Pract Oncol. 2012;3:112–116. - PMC - PubMed
    1. Yoon J., Oh C.W., Kim C.Y. Stevens-johnson syndrome induced by vandetanib. Ann Dermatol. 2011;23:343–345. - PMC - PubMed
    1. Chang C.H., Chang J.W.C., Hui C.Y., Yang C.H. Severe photosensitivity reaction to vandetanib. J Clin Oncol. 2009;27:114–115. - PubMed
    1. Yin Y., Qiu X.Y., Zhang Y.H., Zhang B. A rare cutaneous phototoxic rash after vandetanib therapy in a patient with thyroid cancer: A case report. Medicine (Baltimore) 2019;98:16392. - PMC - PubMed
    1. Fava P., Quaglino P., Fierro M.T., Novelli M., Bernego M.G. Therapeutic hotline. A rare vandetanib-induced photo-allergic drug eruption. Dermatol Ther. 2010;23:553–555. - PubMed

MeSH terms

LinkOut - more resources