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. 1987 Dec;210(3):485-9.
doi: 10.1007/BF00327201.

Strains of Schizosaccharomyces pombe with a disrupted swi1 gene still show some mating-type switching

H Schmidt  1
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Strains of Schizosaccharomyces pombe with a disrupted swi1 gene still show some mating-type switching

H Schmidt. Mol Gen Genet. 1987 Dec.

Abstract

The swi1+ gene is necessary for effective mating-type (MT) switching in Schizosaccharomyces pombe. It was cloned on a 4.2 kb genomic DNA fragment. By site-directed integration into the genome and gene disruption experiments it was proved that the swi1+ gene itself and not a suppressor had been isolated. Disruption of the swi1+ gene causes a phenotype identical to that of the original swi1 mutant, i.e. the strain still shows some MT switching. The swi1 gene is unique in the genome and gives rise to a 3 kb mRNA.

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