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Randomized Controlled Trial
. 2021 Jan-Dec:17:17455065211060637.
doi: 10.1177/17455065211060637.

Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial

Emeka Philip Igbodike  1 , Ibraheem Olayemi Awowole  1 , Olufemi O Kuti  1 , Kayode Olusegun Ajenifuja  1 , George Uchenna Eleje  2 , Simeon Olugbade Olateju  3 , Bolatito Opeyemi Olopade  4 , Omotade Adebimpe Ijarotimi  1 , Emmanuel Oladayo Irek  4 , Njideka Theresa Igbodike  5 , Oluwole Ekundayo Ayegbusi  1 , Joseph Ifeanyichukwu Ikechebelu  2 , Boniface Chukwuneme Okpala  2 , Olabisi Morebisi Loto  1 , Akintunde Olusegun Fehintola  1 , Akinyosoye Deji Ajiboye  1 , Olusola Fajobi  6 , Chima Stephene Abuchi  1 , Uchenna Uchenna Onwudiegwu  1 , Olusola Benjamin Fasubaa  1 , Ernest Okechukwu Orji  1 , Olufemiwa Niyi Makinde  1 , Alexander Tuesday Owolabi  1 , Adebanjo Babalola Adeyemi  1
Affiliations
Randomized Controlled Trial

Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial

Emeka Philip Igbodike et al. Womens Health (Lond). 2021 Jan-Dec.

Abstract

Background: There is no consensus on the preferred time to remove urethral catheter post caesarean section.

Aim: To compare rate of significant bacteriuria and urinary retention following 8-h (study) and 24-h urethral catheter removal (control) post elective caesarean section.

Methods: A randomized controlled trial of eligible participants that underwent elective caesarean section under spinal anaesthesia between March 2019 and November 2019 was conducted. Participants (150 in each arm) were randomly assigned (1:1 ratio) to either 8-h or 24-h group. Primary outcome measures included rates of significant bacteriuria 48-h post-operatively and acute urine retention 6-h post urethral catheter removal. Analysis was by Intention-to-treat. (www.pactr.org:PACTR202105874744483).

Results: There were 150 participants randomized into each arm and data collection was complete. Significant bacteriuria was less in 8-h group (3% versus 6.0%; risk ratio (RR): 0.85 CI: 0.60 to 5.66; p = 0.274), though not significant. Acute urinary retention requiring repeat catheterisation was significantly higher in 8-h group (11(7.3%) versus 0(0.0%); RR: 0.07; CI: 0.87 to 0.97; p = 0.001). Mean time until first voiding was slightly higher in 8-h group (211.4 ± 14.3 min versus 190.0 ± 18.3 min; mean difference (MD): 21.36; CI: -24.36 to 67.08; p = 0.203); but patient in this group had a lower mean time until ambulation (770.0 ± 26.1 min versus 809 ± 26.2 min; MD: -38.8; CI: -111.6 to 34.0; p = 0.300). The 8-h group were significantly more satisfied (82/150 (54.7%) versus 54/150 (36.0%); p = 0.001).

Conclusions: An 8-h group was associated with significant clinical satisfaction and acute urine retention compared to 24-h removal. The timing of urethral catheter removal did not affect rate of significant bacteriuria and other outcomes.

Keywords: acute urine retention; caesarean section; hospital stay; post-operative satisfaction; urethral catheter removal.

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Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

Figures

Figure 1.
Figure 1.
Participants’ flow chart.
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