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. 2021 Nov 23;13(1):184.
doi: 10.1186/s13073-021-01003-9.

Genomic medicine in the Middle East

Ahmad N Abou Tayoun  1   2 , Khalid A Fakhro  3   4 , Alawi Alsheikh-Ali  5   6 , Fowzan S Alkuraya  7
Affiliations

Genomic medicine in the Middle East

Ahmad N Abou Tayoun et al. Genome Med. .

Abstract

We discuss the current state of genomic medicine in Arab countries of the Middle East, a region with outsized contribution to Mendelian genetics due to inbreeding yet has poor representation in global variome datasets. We focus on genomic testing, clinical genetics, and genetic counseling services along with associated training and research programs. Finally, we highlight opportunities for improvement in genomic medicine services in this region.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, et al. The complete sequence of a human genome. BioRxiv. 10.1101/2021.05.26.445798.
    1. Green ED, Gunter C, Biesecker LG, Francesco VD, Easter CL, Feingold EA, et al. Strategic vision for improving human health at The Forefront of Genomics. Nature. 2020;586(7831):683–692. doi: 10.1038/s41586-020-2817-4. - DOI - PMC - PubMed
    1. Shamia A, Shaheen R, Sabbagh N, Almoisheer A, Halees A, Alkuraya FS. Revisiting disease genes based on whole-exome sequencing in consanguineous populations. Hum Genet. 2015;134(9):1029–1034. doi: 10.1007/s00439-015-1580-3. - DOI - PubMed
    1. Saadallah AA, Rashed MS. Newborn screening: experiences in the Middle East and North Africa. J Inherit Metab Dis. 2007;30(4):482–489. doi: 10.1007/s10545-007-0660-5. - DOI - PubMed
    1. Arrayed S. AL. Campaign to control genetic blood diseases in Bahrain. Community Genet. 2005;8(1):52–55. doi: 10.1159/000083340. - DOI - PubMed