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Review
. 2022 Mar;49(4):1200-1210.
doi: 10.1007/s00259-021-05622-7. Epub 2021 Nov 24.

Supramolecular biomaterials for bio-imaging and imaging-guided therapy

Beibei Xie #  1 , Yuan-Fu Ding #  1 , Mingju Shui  1 , Ludan Yue  1 , Cheng Gao  1   2 , Ian W Wyman  3 , Ruibing Wang  4   5
Affiliations
Review

Supramolecular biomaterials for bio-imaging and imaging-guided therapy

Beibei Xie et al. Eur J Nucl Med Mol Imaging. 2022 Mar.

Abstract

Benefiting from their unique advantages, including reversibly switchable structures, good biocompatibility, facile functionalization, and sensitive response to biological stimuli, supramolecular biomaterials have been widely applied in biomedicine. In this review, the representative achievements and trends in the design of supramolecular biomaterials (mainly those derived from biomacromolecules) with specific macromolecules including peptides, deoxyribonucleic acid, and polysaccharides, as well as their applications in bio-imaging and imaging-guided therapy are summarized. This review will serve as an important summary and "go for" reference for explorations of the applications of supramolecular biomaterials in bio-imaging and image-guided therapy, and will promote the development of supramolecular chemistry as an emerging interdisciplinary research area.

Keywords: Bio-imaging; Biofunctional materials; Supramolecular chemistry; Therapy.

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