Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Mar;104(3):e60-e63.
doi: 10.1308/rcsann.2021.0141. Epub 2021 Nov 25.

Glomus tumour of the nipple in a male patient

Z Al-Ishaq  1 , U Asif  1 , M Roy  2 , O Sikdar  3 , A Bhatnagar  1 , T Sircar  1
Affiliations
Case Reports

Glomus tumour of the nipple in a male patient

Z Al-Ishaq et al. Ann R Coll Surg Engl. 2022 Mar.

Abstract

A glomus tumour is a benign mesenchymal tumour. It is extremely rare in the breast. We report a case of glomus tumour of the nipple in a 54-year-old man. To the best of the authors' knowledge, this is the first case report of a glomus tumour of the nipple. We describe the different presenting symptoms, method of diagnosis and treatment.

Keywords: Breast; Glomus tumour; Male; Nipple.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(a) Left nipple showing a 1cm pigmented lesion at the tip. (b) The lesion protruded from the tip of the nipple with dried crust at its end.
Figure 2
Figure 2
(a) Two fragments of skin-covered tissue (long arrow) with tumour in the dermis (short arrow). (2× magnification.) (b) The tumour is composed of cords of glomus cells (arrowhead) in hyalinised stroma with interspersed capillary-sized blood vessels (arrow). Haematoxylin and eosin stain (20× multiplication).
Figure 3
Figure 3
AE1/AE3 (pan-cytokeratin immunostain) stains the overlying epidermis brown but the tumour cells in the dermis are negative (arrow) (10× multiplication)
Figure 4
Figure 4
The glomus cells are positive with smooth muscle actin immunostain and stain brown (10× multiplication)
Figure 5
Figure 5
Glomus cells are negative with S100 stain
See this image and copyright information in PMC

References

    1. Gombos Z, Zhang PJ. Glomus tumor. Arch Pathol Lab Med 2008; 132: 1448–1452.10.5858/2008-132-1448-GT - DOI - PubMed
    1. Mizutani L, Tanaka Y, Kondo Yet al. . Glomus tumor of a female breast: a case report and review of the literature. J Med Ultrason 2014; 41: 385–388.10.1007/s10396-013-0517-5 - DOI - PubMed
    1. Crandall GA, Jones GE. Glomus body tumor of the breast: a rare cause of isolated breast pain. Plast Reconstr Surg 2013; 132: 1087e–1088e.10.1097/PRS.0b013e3182a9803f - DOI - PubMed
    1. El Khoury M, Tran-Tranh D, Terrone Det al. . Case 201: glomus tumor of the breast. Radiology 2014; 270: 302–306.10.1148/radiol.13120919 - DOI - PubMed
    1. Ward RC, Donegan L, Wang Yet al. . Glomangioma of the male breast. Breast J 2018; 24: 87–89.10.1111/tbj.12840 - DOI - PubMed

Publication types