Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;47(2):206-209.
doi: 10.1139/apnm-2021-0500. Epub 2021 Nov 25.

Five-year changes in objectively measured cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late adulthood

Ryan J Dougherty  1   2 , Sarah R Lose  2 , Julian M Gaitán  2 , Brandon M Mergen  2 , Nathaniel A Chin  2 , Ozioma C Okonkwo  2   3   4 , Dane B Cook  5   6
Affiliations

Five-year changes in objectively measured cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late adulthood

Ryan J Dougherty et al. Appl Physiol Nutr Metab. 2022 Feb.

Abstract
in English, French

This study examined 5-year changes in cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late aged adults. Fifty-seven participants completed baseline and follow-up treadmill exercise tests and physical activity monitoring. We observed a 14% decline in fitness (p < 0.001), 12% decrease in physical activity (p = 0.010), and non-significant increase in sedentary time (p = 0.196). Age was negatively associated with 5-year change in physical activity (r = -0.31; p = 0.02) and this decline was strongest among APOE ε4 carriers (g = -0.75). Novelty: Cardiorespiratory fitness and physical activity significantly declined from mid-to-late adulthood, these findings were most pronounced among older adults and those with genetic risk for Alzheimer's disease.

Cette étude a examiné les changements sur cinq ans de l’aptitude cardiorespiratoire, de l’activité physique et du temps sédentaire chez les adultes d’âge moyen à avancé. Cinquante-sept participants ont effectué des tests de base et de suivi consistant en un exercice sur tapis roulant et se sont soumis à une surveillance de l’activité physique. Nous avons observé une baisse de 14 % de l’aptitude physique (p < 0,001), une diminution de 12 % de l’activité physique (p = 0,010) et une augmentation non significative du temps sédentaire (p = 0,196). L’âge était négativement associé à une variation sur cinq ans de l’activité physique (r = −0,31; p = 0,02) et cette baisse était la plus forte parmi les porteurs APOE ε4 (g = −0,75). [Traduit par la Rédaction]

Les nouveautés ::

  1. L’aptitude cardiorespiratoire et l’activité physique ont considérablement diminué de l’âge moyen à l’âge avancé, ces résultats étaient plus prononcés chez les personnes âgées et celles présentant un risque génétique de maladie d’Alzheimer.

Keywords: accelerometer; accéléromètre; aerobic fitness; apolipoprotein E4; apolipoprotéine E4; aptitude aérobie; condition physique; exercice physique; exercise; facteur de risque; facteurs liés au mode de vie; lifestyle factors; longitudinal assessment; physical fitness; risk factor; évaluation longitudinale.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Baba R, Nagashima M, Goto M, Nagano Y, Yokota M, Tauchi N, and Nishibata K 1996. Oxygen uptake efficiency slope: a new index of cardiorespiratory functional reserve derived from the relation between oxygen uptake and minute ventilation during incremental exercise. J. Am. Coll. Cardiol 28(6): 1567–1572. doi:10.1016/S0735-1097(96)00412-3. - DOI - PubMed
    1. Caspersen CJ, Pereira MA, and Curran KM 2000. Changes in physical activity patterns in the United States, by sex and cross-sectional age. Med. Sci. Sports Exerc 32(9): 1601–1609. doi:10.1097/00005768-200009000-00013. - DOI - PubMed
    1. Dougherty RJ, Ellingson LD, Schultz SA, Boots EA, Meyer JD, Lindheimer JB, et al. 2016. Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer’s disease. Alzheimer’s Dement. 4: 14–17. doi:10.1016/j.dadm.2016.03.005. - DOI - PMC - PubMed
    1. Dougherty RJ, Schultz SA, Boots EA, Ellingson LD, Meyer JD, Van Riper S, et al. 2017a. Relationships between cardiorespiratory fitness, hippocampal volume, and episodic memory in a population at risk for Alzheimer’s disease. Brain Behav. 7(3): e00625. doi:10.1002/brb3.625. - DOI - PMC - PubMed
    1. Dougherty RJ, Schultz SA, Kirby TK, Boots EA, Oh JM, Edwards D, et al. 2017b. Moderate physical activity is associated with cerebral glucose metabolism in adults at risk for Alzheimer’s disease. J. Alzheimers Dis 58(4): 1089–1097. doi:10.3233/JAD-161067. - DOI - PMC - PubMed

Substances