doi: 10.1016/0005-2736(78)90019-6.
Microviscosity changes during differentiation of neuroblastoma cells
- PMID: 348237
- DOI: 10.1016/0005-2736(78)90019-6
Item in Clipboard
Microviscosity changes during differentiation of neuroblastoma cells
Biochim Biophys Acta.
.
Abstract
Microviscosity (eta) of the plasma-membrane lipid matrix was measured in exponentially growing and differentiating C1300 mouse neuroblastoma cells, attached to a glass substratum, by fluorescence polarisation of 1,6-diphenyl-1,3,5-hexatriene. Upon differentiation eta decreases progressively, reaching values below those observed in the growth phase. Treatment of the cells with dipalmitoyl phosphatidylcholine vesicles reversibly inhibits morphological differentiation. The results show that a high membrane fluidity is a prerequisite for differentiation.
Similar articles
-
Microviscosity modulation during the cell cycle of neuroblastoma cells.Proc Natl Acad Sci U S A. 1977 Oct;74(10):4458-61. doi: 10.1073/pnas.74.10.4458. Proc Natl Acad Sci U S A. 1977. PMID: 270690 Free PMC article.
-
A change in membrane microviscosity of mouse neuroblastoma cells in association with morphological differentiation.Biochim Biophys Acta. 1978 Jun 2;509(3):440-9. doi: 10.1016/0005-2736(78)90238-9. Biochim Biophys Acta. 1978. PMID: 656420
-
Enveloped viruses as model membrane systems: microviscosity of vesicular stomatitis virus and host cell membranes.Biochemistry. 1976 Aug 10;15(16):3563-70. doi: 10.1021/bi00661a026. Biochemistry. 1976. PMID: 182211
-
Lipid composition and microviscosity of subcellular fractions from rabbit thymocytes. Differences in the microviscosity of plasma membranes from subclasses of thymocytes.Biochim Biophys Acta. 1979 Sep 4;556(1):17-37. doi: 10.1016/0005-2736(79)90416-4. Biochim Biophys Acta. 1979. PMID: 476116
-
The plasma membrane as a regulatory site in growth and differentiation of neuroblastoma cells.Int Rev Cytol. 1982;74:1-54. doi: 10.1016/s0074-7696(08)61168-7. Int Rev Cytol. 1982. PMID: 6288609 Review. No abstract available.
Cited by
-
Biochemical and cellular aspects of the anticancer activity of selenium.Biol Trace Elem Res. 1988 Jan-Apr;15:243-55. doi: 10.1007/BF02990141. Biol Trace Elem Res. 1988. PMID: 2484522
-
Lateral diffusion of membrane lipids and proteins during the cell cycle of neuroblastoma cells.Proc Natl Acad Sci U S A. 1980 Mar;77(3):1526-8. doi: 10.1073/pnas.77.3.1526. Proc Natl Acad Sci U S A. 1980. PMID: 6929504 Free PMC article.
-
Complete microviscosity maps of living plant cells and tissues with a toolbox of targeting mechanoprobes.Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18110-18118. doi: 10.1073/pnas.1921374117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669427 Free PMC article.
-
Role of the growth cone in neuronal differentiation.Mol Neurobiol. 1989 Spring-Summer;3(1-2):101-33. doi: 10.1007/BF02935590. Mol Neurobiol. 1989. PMID: 2679766 Review.
-
Differentiated neuroblastoma cells are more susceptible to aluminium toxicity than developing cells.Arch Toxicol. 1989;63(3):231-7. doi: 10.1007/BF00316374. Arch Toxicol. 1989. PMID: 2764711
MeSH terms
LinkOut - more resources
Full Text Sources
