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Review
. 2022 Feb;42(1):121-144.
doi: 10.1016/j.iac.2021.10.001.

Anaphylaxis to Drugs, Biological Agents, and Vaccines

Ruchi H Shah  1 , Margaret M Kuder  1 , David M Lang  2
Affiliations
Review

Anaphylaxis to Drugs, Biological Agents, and Vaccines

Ruchi H Shah et al. Immunol Allergy Clin North Am. 2022 Feb.

Abstract

Anaphylaxis is a multi-system syndrome resulting from the release of mediators from mast cells and basophils. Drugs are common causes. Anaphylaxis to certain drugs, vaccines, and biological agents present clinical challenges, and merit referral to a board-certified allergist/immunologist for further evaluation and management.

Keywords: Anaphylaxis; Aspirin-exacerbated respiratory disease; Contrast-induced anaphylaxis; Drug-induced anaphylaxis; NSAID-Induced anaphylaxis; Vaccine-induced anaphylaxis.

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Conflict of interest statement

Disclosures R. H. Shah, MD, and M. M. Kuder, MD, have nothing to disclose. D. M. Lang, MD, has received honoraria from, has served as a consultant for, and/or has carried out clinical research with: Astra Zeneca, Sanofi-Regeneron, National Institute of Allergy and Infectious Diseases.

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