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Review
. 2022 Feb;42(1):77-90.
doi: 10.1016/j.iac.2021.09.006.

Management of Anaphylaxis in Infants and Toddlers

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Review

Management of Anaphylaxis in Infants and Toddlers

Nicole Ramsey et al. Immunol Allergy Clin North Am. 2022 Feb.

Abstract

Anaphylaxis is a systemic allergic reaction that can be caused by food, drugs, insect bites, or unknown triggers in infants and toddlers. Anaphylaxis rates are increasing. Infants and toddlers may have increased exposure to known and unknown allergens, decreased ability to describe their symptoms, and an expanded differential diagnosis for consideration on presentation. The most common symptoms in these age groups are cutaneous and gastrointestinal. Age-specific language may be helpful for caregivers to identify and describe the symptoms of anaphylaxis in infants and toddlers. Long-term management of anaphylaxis includes allergy evaluation to guide avoidance and assess prognosis and education on allergic reaction management; this incorporates the prescription of epinephrine autoinjector and provision of an allergy emergency plan.

Keywords: Anaphylaxis; Food allergy; Infant; Management; Prevention; Toddler.

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Conflict of interest statement

Disclosure N. Ramsey – Nothing to disclose, J. Wang receives research support from the NIAID, Aimmune, DBV Technologies, and Regeneron, and has received consultancy fees from ALK Abello, DBV Technologies, and Genentech.

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