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. 2022 Feb 10;59(2):2102463.
doi: 10.1183/13993003.02463-2021. Print 2022 Feb.

Risk factors for mortality in patients with COVID-19 needing extracorporeal respiratory support

Affiliations

Risk factors for mortality in patients with COVID-19 needing extracorporeal respiratory support

Jordi Riera et al. Eur Respir J. .

Abstract

When indicating ECMO in patients with COVID-19, centre case volume, age, driving pressure and the duration of symptoms (not the length of MV) should be taken into account. Large drainage cannula and high PEEP levels during the first days are recommended. https://bit.ly/3DGjGkk

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Conflict of interest statement

Conflict of interest: The authors declare that they have no conflict of interest.

Figures

FIGURE 1
FIGURE 1
a) Cox model including relevant factors and its association with hospital mortality in critically ill COVID-19 patients with extracorporeal respiratory support. Kaplan–Meier survival estimates according to b) pre-ECMO mechanical ventilation days, c) age categories and d) centre case volume. HR: hazard ratio; ECMO: extracorporeal membrane oxygenation; MV: mechanical ventilation; PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; FIO2: fraction of inspired oxygen; bpm: breaths per min; Fr: french; PEEP: positive end-expiratory pressure.

Comment in

References

    1. Henry BM, Lippi G. Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): pooled analysis of early reports. J Crit Care 2020; 58: 27–28. doi:10.1016/j.jcrc.2020.03.011 - DOI - PMC - PubMed
    1. Barbaro RP, MacLaren G, Boonstra PS, et al. . Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet 2020; 396: 1071–1078. doi:10.1016/S0140-6736(20)32008-0 - DOI - PMC - PubMed
    1. Broman LM, Eksborg S, Coco VL, et al. . Extracorporeal membrane oxygenation for COVID-19 during first and second waves. Lancet Respir Med 2021; 9: e80–e81. doi:10.1016/S2213-2600(21)00262-9 - DOI - PMC - PubMed
    1. Riera J, Roncon-Albuquerque R, Fuset MP, et al. . Increased mortality in patients with COVID-19 receiving extracorporeal respiratory support during the second wave of the pandemic. Intensive Care Med 2021; 47: 1490–1493. - PMC - PubMed
    1. Combes A, Hajage D, Capellier G, et al. . Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med 2018; 378: 1965–1975. doi:10.1056/NEJMoa1800385 - DOI - PubMed