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Review
. 2021 Nov 11;9(11):1662.
doi: 10.3390/biomedicines9111662.

miRNAs and lncRNAs: Potential Non-Invasive Biomarkers for Endometriosis

Affiliations
Review

miRNAs and lncRNAs: Potential Non-Invasive Biomarkers for Endometriosis

Ioana Maria Maier et al. Biomedicines. .

Abstract

Many studies have tried to understand the mechanism of endometriosis and its manner of manifestation. However, the only method of diagnosis considered as the gold standard in endometriosis is an invasive method called exploratory laparoscopy. Hence, there is a need to identify non-invasive or minimally invasive methods to minimize patients' suffering, thus increasing their addressability at the earliest possible staging of the disease, and to diagnose this condition as soon as possible. miRNAs (microRNAs) and lncRNAs (long-noncoding RNAs) are potential non-invasive diagnostic methods for endometriosis. Multiple clinical trials indicate that miRNA can be used as a non-invasive method in the diagnosis and differentiation of endometriosis stages.

Keywords: endometriosis; lncRNAs; miRNAs.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

    1. Brosens I., Benagiano G. Endometriosis, a modern syndrome. Indian J. Med. Res. 2011;133:581–593. - PMC - PubMed
    1. Brătilă E., Comandașu D., Coroleucă C.A., Cîrstoiu M.M., Bohîlţea R., Mehedinţu C., Vlădăreanu S., Berceanu C. Gastrointestinal symptoms in endometriosis correlated with the disease stage; Proceedings of the XXXVIth National Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Filodiritto Editore; Cluj Napoca, Romania. 8–11 June 2016; pp. 67–71.
    1. Nisolle M., Donnez J. Peritoneal Endometriosis, Ovarian Endometriosis, and Adenomyotic Nodules of the Rectovaginal Septum Are Three Different Entities. Fertil. Steril. 1997;68:585–596. doi: 10.1016/S0015-0282(97)00191-X. - DOI - PubMed
    1. Taylor H.S. Endometriosis: A complex systemic disease withmultiple manifestations. Fertil. Steril. 2019;112:235–236. doi: 10.1016/j.fertnstert.2019.06.006. - DOI - PubMed
    1. Vallvé-Juanico J., Houshdaran S., Giudice L.C. The endometrial immune environment of women with endometriosis. Hum. Reprod. Update. 2019;25:565–592. doi: 10.1093/humupd/dmz018. - DOI - PMC - PubMed

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