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Review
. 2021 Nov 12;10(22):5258.
doi: 10.3390/jcm10225258.

Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature

Maria Irene Bellini  1   2 , Marco Biffoni  2 , Renato Patrone  3 , Maria Carola Borcea  2 , Maria Ludovica Costanzo  2 , Tiziana Garritano  2 , Rossella Melcarne  2 , Rosa Menditto  2 , Alessio Metere  4 , Chiara Scorziello  2 , Marco Summa  2 , Luca Ventrone  2 , Vito D'Andrea  2 , Laura Giacomelli  2
Affiliations
Review

Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature

Maria Irene Bellini et al. J Clin Med. .

Abstract

There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as 'poorly differentiated thyroid carcinoma' (PDTC), or 'insular carcinoma', in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature.

Keywords: fine-needle aspiration cytology; poorly differentiated thyroid cancer; total thyroidectomy.

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Conflict of interest statement

The authors declare no conflict of interest.

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