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Review
. 2021 Nov 18;14(22):6994.
doi: 10.3390/ma14226994.

Surface Modification to Modulate Microbial Biofilms-Applications in Dental Medicine

Alina-Maria Holban  1   2 , Catalina Farcasiu  3 , Oana-Cella Andrei  3 , Alexandru Mihai Grumezescu  2   4   5 , Alexandru-Titus Farcasiu  3
Affiliations
Review

Surface Modification to Modulate Microbial Biofilms-Applications in Dental Medicine

Alina-Maria Holban et al. Materials (Basel). .

Abstract

Recent progress in materials science and nanotechnology has led to the development of advanced materials with multifunctional properties. Dental medicine has benefited from the design of such materials and coatings in providing patients with tailored implants and improved materials for restorative and functional use. Such materials and coatings allow for better acceptance by the host body, promote successful implantation and determine a reduced inflammatory response after contact with the materials. Since numerous dental pathologies are influenced by the presence and activity of some pathogenic microorganisms, novel materials are needed to overcome this challenge as well. This paper aimed to reveal and discuss the most recent and innovative progress made in the field of materials surface modification in terms of microbial attachment inhibition and biofilm formation, with a direct impact on dental medicine.

Keywords: advanced materials; bacteria attachment; biofilm modulation; dental plaque; nano-modified surfaces.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Antibacterial mechanisms in advanced dental materials. ROS = reactive oxygen species.
Figure 2
Figure 2
Surface modifications in dental materials investigated for their enhanced antibacterial activity. Upper part of the figure (pale green) shows different types of surface modifications which can be applied to various dental materials (i.e., metals and ceramics or polymers).
See this image and copyright information in PMC

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