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Review
. 2021 Nov 5;57(11):1208.
doi: 10.3390/medicina57111208.

Pharmacological Treatment for Acute Traumatic Musculoskeletal Pain in Athletes

Alessandro de Sire  1 , Nicola Marotta  1 , Lorenzo Lippi  2 , Dalila Scaturro  3 , Giacomo Farì  4 , Alfonso Liccardi  5 , Lucrezia Moggio  1 , Giulia Letizia Mauro  3 , Antonio Ammendolia  1 , Marco Invernizzi  2   6
Affiliations
Review

Pharmacological Treatment for Acute Traumatic Musculoskeletal Pain in Athletes

Alessandro de Sire et al. Medicina (Kaunas). .

Abstract

Pain management is a crucial issue for athletes who train and compete at the highest performance levels. There are still evidence gaps for the use of analgesics for sports injuries despite the growing interest in training and competition settings. However, high-quality research is needed to determine the most appropriate and optimal timing and formulations in non-steroidal anti-inflammatory drug and opioid management, particularly given the strictness of anti-doping regulations. Indeed, the role of pharmacological therapy in reducing acute traumatic pain in athletes should still be addressed to minimize the timing of return to sport. Therefore, the aim of this comprehensive review was to summarize the current evidence about pain management in the setting of acute injury in elite athletes, providing the most informed strategy for pain relief and performance recovery.

Keywords: athletic injuries; pain management; rehabilitation; return to sport; sport medicine; trauma.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Main sports-related traumatic musculoskeletal injuries (graphical model and magnetic resonance imaging).
See this image and copyright information in PMC

References

    1. Warburton D.E., Nicol C.W., Bredin S.S. Health benefits of physical activity: The evidence. CMAJ. 2006;174:801–809. doi: 10.1503/cmaj.051351. - DOI - PMC - PubMed
    1. de Sire A., Marotta N., Marinaro C., Curci C., Invernizzi M., Ammendolia A. Role of Physical Exercise and Nutraceuticals in Modulating Molecular Pathways of Osteoarthritis. Int. J. Mol. Sci. 2021;22:5722. doi: 10.3390/ijms22115722. - DOI - PMC - PubMed
    1. Farì G., Di Paolo S., Ungaro D., Luperto G., Farì E., Latino F. The Impact of COVID-19 on Sport and Daily Activities in an Italian Cohort of Football School Children. Int. J. Athl. Ther. Train. 2021;26:1–5. doi: 10.1123/ijatt.2020-0066. - DOI
    1. Notarnicola A., Covelli I., Maccagnano G., Marvulli R., Mastromauro L., Ianieri G., Boodhoo S., Turitto A., Petruzzella L., Farì G., et al. Extracorporeal shockwave therapy on muscle tissue: The effects on healthy athletes. J. Biol. Regul. Homeost. Agents. 2018;32:185–193. - PubMed
    1. Carder S.L., Giusti N.E., Vopat L.M., Tarakemeh A., Baker J., Vopat B.G., Mulcahey M.K. The Concept of Sport Sampling Versus Sport Specialization: Preventing Youth Athlete Injury: A Systematic Review and Meta-analysis. Am. J. Sports Med. 2020;48:2850–2857. doi: 10.1177/0363546519899380. - DOI - PubMed