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. 2021 Oct 25;11(11):1085.
doi: 10.3390/jpm11111085.

Standardized Comparison of Cardiovascular Risk Factors Prevalence in Spanish Women and Men Living with HIV and in the General Population

Anna Camps-Vilaró  1   2 , Silvia Pérez-Fernández  1   3 , Isaac Subirana  1   2 , Ramon Teira  4 , Vicente Estrada  5 , Pere Domingo  6 , Irene R Dégano  1   2   7 , Jaume Marrugat  1   2
Affiliations

Standardized Comparison of Cardiovascular Risk Factors Prevalence in Spanish Women and Men Living with HIV and in the General Population

Anna Camps-Vilaró et al. J Pers Med. .

Abstract

People living with HIV (PLWH) have an increased risk of cardiovascular (CV) disease, likely due to a higher prevalence of CV risk factors. We compared the age-standardized prevalence and management of CV risk factors in PLWH to that of the general population in Spain. Blood pressure, lipid, glucose, and anthropometric profiles were cross-sectionally compared along with the treatment of hypertension, dyslipidemia, and diabetes in a general population cohort and a PLWH cohort. Prevalence rates were standardized by the direct method by 10-year age groups in European standard populations and stratified by gender. We included 47,593 individuals aged 35 to 74 years, 28,360 from the general population cohort and 19,233 from the PLWH cohort. Compared to the general population, PLWH had a higher concentration of triglycerides (>35 mg/dL in women and >26 mg/dL in men) and a higher prevalence of smoking (>23% and >17%) and diabetes (>9.9% and >8.5%). The prevalence of treated diabetes, hypertension, and dyslipidemia were up to three-fold lower in both women and men living with HIV. There was a significant difference in PLWH compared to the general population in the lipid, glucose, and anthropometric profile. In addition, PLWH were less often treated for diagnosed diabetes, hypertension, and dyslipidemia.

Keywords: HIV; cardiovascular risk factor; general population; people living with HIV; prevalence.

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Conflict of interest statement

J.M. reports grants and consultancy fees from AstraZeneca, Sanofi, Shire, Gilead, Daichii-Sankyo, Genincode, and Ferrer. The other authors declare no conflict of interest.

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