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Review
. 2021 Nov 19;13(11):4148.
doi: 10.3390/nu13114148.

Relationship between Dietary Patterns with Benign Prostatic Hyperplasia and Erectile Dysfunction: A Collaborative Review

Giorgio Ivan Russo  1 , Giuseppe Broggi  2 , Andrea Cocci  3 , Paolo Capogrosso  4 , Marco Falcone  5 , Ioannis Sokolakis  6 , Murat Gül  7 , Rosario Caltabiano  2 , Marina Di Mauro  8
Affiliations
Review

Relationship between Dietary Patterns with Benign Prostatic Hyperplasia and Erectile Dysfunction: A Collaborative Review

Giorgio Ivan Russo et al. Nutrients. .

Abstract

Interest in the role of dietary patterns has been consistently emerging in recent years due to much research that has documented the impact of metabolism on erectile dysfunction (ED) and/or benign prostatic hyperplasia (BPH). We conducted a non-systematic review of English articles published from 1964 to September 2021. The search terms were: ("dietary patterns" OR "diet") AND/OR ("erectile dysfunction") AND/OR ("benign prostatic hyperplasia"). In the present review, we have highlighted how the association between dietary patterns and two of the most frequent pathologies in urology, namely erectile dysfunction and benign prostatic hyperplasia, is present in the literature. The data suggested that a diet that is more adherent to the Mediterranean diet or that emphasizes the presence of vegetables, fruits, nuts, legumes, and fish or other sources of long-chain (n-3) fats, in addition to reduced content of red meat, may have a beneficial role on erectile function. At the same time, the same beneficial effects can be transferred to BPH as a result of the indirect regulatory effects on prostatic growth and smooth muscle tone, thus determining an improvement in symptoms. Certainly, in-depth studies and translational medicine are needed to confirm these encouraging data.

Keywords: benign prostatic hyperplasia; diet; erectile dysfunction; metabolism; prostate.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Overview of mechanisms associated with erectile dysfunction.
Figure 2
Figure 2
Relationship between dietary patterns and erectile dysfunction. Relationship between dietary patterns and erectile dysfunction. PDE5 = phosphodiesterase-5 inhibitors; ADA = adenosine deaminase; NO = nitrogen oxide; MDA = Malondialdehyde; ED = erectile dysfunction.
Figure 3
Figure 3
Overview of mechanisms associated with benign prostatic hyperplasia.
Figure 4
Figure 4
Relationship between dietary patterns and BPH. Relationship between dietary patterns and BPH. STAT3 = Signal Transducer And Activator Of Transcription 3; BPH = benign prostatic hyperplasia.
See this image and copyright information in PMC

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