Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Sep;16(5):1346-1347.
doi: 10.1177/19322968211060069. Epub 2021 Nov 29.

Response to Comment on "Minimal and Maximal Models to Quantitate Glucose Metabolism: Tools to Measure, to Simulate and to Run in Silico Clinical Trials"

Affiliations
Comment

Response to Comment on "Minimal and Maximal Models to Quantitate Glucose Metabolism: Tools to Measure, to Simulate and to Run in Silico Clinical Trials"

Claudio Cobelli et al. J Diabetes Sci Technol. 2022 Sep.
No abstract available

Keywords: glucose effectiveness; insulin sensitivity; numerical identifiability; oral minimal model; structural identifiability.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Comment on

References

    1. Eichenlaub M, Saccomani MP, Hattersley JG, Khovanova NA. Minimal and maximal models to quantitate glucose metabolism: tools to measure, to simulate and to run in silico clinical trials [published online ahead of print May 25, 2021]. J Diab Sci Technol. doi: 10.1177/19322968211015268. - DOI - PMC - PubMed
    1. Dalla Man C, Caumo A, Cobelli C. The oral glucose minimal model: estimation of insulin sensitivity from a meal test. IEEE Trans Biomed Eng. 2002;49(5):419-429. - PubMed
    1. Dalla Man C, Yarasheski KE, Caumo A, et al. Insulin sensitivity by oral glucose minimal models: validation against clamp. Am J Physiol Endocrinol Metab. 2005;289:E954-E959. - PubMed
    1. Dalla Man C, Caumo A, Basu R, Rizza R, Toffolo G, Cobelli C. Minimal model estimation of glucose absorption and insulin sensitivity from an oral test: validation with a tracer method. Am J Physiol Endocrinol Metab. 2004;287:E637-E643. - PubMed
    1. Basu A, Dalla Man C, Basu R, Toffolo G, Cobelli C, Rizza RA. Effects of Type 2 diabetes on insulin secretion, insulin action, glucose metabolism. Diabetes Care. 2009;32:866-872. - PMC - PubMed