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Case Reports
. 2021 Oct;11(5):e732-e735.
doi: 10.1212/CPJ.0000000000000937.

Overnight Ictal Magnetoencephalography

Jeremy T Moreau  1 , Elisabeth Simard-Tremblay  1 , Steffen Albrecht  1 , Bernard Rosenblatt  1 , Sylvain Baillet  1 , Roy W R Dudley  1
Affiliations
Case Reports

Overnight Ictal Magnetoencephalography

Jeremy T Moreau et al. Neurol Clin Pract. 2021 Oct.
No abstract available

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Figures

Figure 1
Figure 1. Case 1 Ictal MEG and Pathology
(A) Reduced montage (76 of 275 MEG channels displayed) showing the seizure onset, followed by movement artefact. (B) Magnetic source imaging of preop ictal MEG overlaid on postop MRI. (C) Preop T1 MRI showing blurring of the gray-white matter junction in an area colocalizing with the MEG seizure onset zone. (D–F) Surgical pathology consisting of cortex and subcortical white matter from the resected anterior aspect of the superior temporal gyrus showing FCD type IIa. (G) Surgical pathology consisting of cortex and subcortical white matter from the resected posterior aspect of the superior temporal gyrus showing rare dysmorphic neurons, but no frank FCD. (D) H&E 10x. (E) NeuN 10x. (F) SMI-32 20x. (G) H&E 20x. FCD = focal cortical dysplasia; MEG = magnetoencephalography.
Figure 2
Figure 2. Case 2 Ictal MEG, FDG PET, and SEEG
(A) MEG source imaging over 5 s windows of the seizure in (B) showing ictal spread beginning in the left supramarginal gyrus. (B) Reduced montage (76 of 275 MEG channels displayed) showing seizure onset and spread. (C) MEG source imaging of seizure onset in 9 independent seizures (4 L parietal, 3 L frontal, 1 L inferior temporal, 1 R occipital) captured during the overnight ictal MEG. Five seizures were excluded because of artefact or missed onset. Each color represents a different seizure. (D) Ictal MEG source imaging plotted over first SEEG postimplantation MRI. SEEG electrodes are shown in gray, with green channel labels. (E) 18F-FDG PET showing diffuse left hemispheric hypometabolism. MEG = magnetoencephalography.
See this image and copyright information in PMC

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