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Case Reports
. 2021 Oct;11(5):e777-e780.
doi: 10.1212/CPJ.0000000000000973.

Wernicke Encephalopathy in Children

Affiliations
Case Reports

Wernicke Encephalopathy in Children

Andreia Forno et al. Neurol Clin Pract. 2021 Oct.
No abstract available

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Figures

Figure 1
Figure 1. Case 1. Day 35 Brain MRI (A–I). Two Months Follow-up Brain MRI (J)
(A, B) Axial T2-weighted images showing bilateral and symmetrical hypersignal in the mammillary bodies (arrows, a), tectal plate (arrow heads, a), dorsomedial thalami (arrow heads, b), and putamina (arrows, b). (C, D) Axial FLAIR images showing symmetrical hypersignal in the caudate nucleus (arrows, c) and frontal cerebral cortex (d). (E, F) Diffusion weighted imaging and apparent diffusion coefficient map demonstrating restricted diffusion in the head of the caudate nucleus (arrows). (G) Sagittal T1-weighted image showing hyposignal in the mammillary bodies (arrow head). (H, I) Axial T1-weighted contrast-enhanced images showing postcontrast enhancement in the mammillary bodies (arrows, h), periaqueductal gray matter, tectal plate (arrow heads, h), and dorsomedial thalami (arrow heads, i). (J) Two months of follow-up MRI. Sagittal T1-weighted image showing marked atrophy of the mammillary bodies (arrow head).
Figure 2
Figure 2. Case 2. Brain MRI
(A, B) Axial FLAIR images showing bilateral and symmetrical hypersignal in the mammillary bodies (arrows, a) and tectal plate (arrows, b). (C) Sagittal T1-weighted image showing hyposignal in the mammillary bodies (arrow head).

References

    1. Chandrakumar A ,Bhardwaj A, t Jong GW. Review of thiamine deficiency disorders: Wernicke encephalopathy and Korsakoff psychosis. J Basic Clin Physiol Pharmacol 2018;30:153–162. - PubMed
    1. Galvin R, Bråthen G, Ivashynka A, et al. . EFNS guidelines for diagnosis, therapy and presention of Wernicke encephalopathy. Eur J Neurol 2010;17:1408–1418. - PubMed
    1. Lallas M, Desai J. Wernicke encephalopathy in children and adolescentes. World J Pediatr 2014;10:293–298. - PubMed
    1. Vasconcelos MM, Silva KP, Vidal G, Silva AF, Domingues RC, Berditchevsky CR. Early diagnosis of pediatric Wernicke's encephalopathy. Pediatr Neurol 1999;20:289–294. - PubMed
    1. Zuccoli G, Pipitone N. Neuroimaging findings in acute Wernicke's Encephalopathy: review of the Literature. AJR Am J Roentgenol 2009;192:501–508. - PubMed

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