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. 2022 Mar 1;176(3):313-316.
doi: 10.1001/jamapediatrics.2021.4807.

Human Papillomavirus Vaccination and Trends in Cervical Cancer Incidence and Mortality in the US

Tara Tabibi  1 , Justin M Barnes  2 , Aneri Shah  1 , Nosayaba Osazuwa-Peters  3 , Kimberly J Johnson  4 , Derek S Brown  4
Affiliations

Human Papillomavirus Vaccination and Trends in Cervical Cancer Incidence and Mortality in the US

Tara Tabibi et al. JAMA Pediatr. .

Abstract

This cohort study examines the association of human papillomvirus vaccination with cervical cancer incidence and mortality rates in the US, comparing age groups understood to have differing levels of vaccination.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Temporal Patterns in Cervical Cancer Incidence and Mortality
Cervical cancer incidence and mortality rates from 2001 through 2017 among girls and women aged 15 to 39 years are shown, separated by age subgroups. Data sources: Combined Surveillance, Epidemiology, and End Results and National Program of Cancer Registries databases (incidence) and National Center for Health Statistics (mortality).
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References

    1. Guo F, Cofie LE, Berenson AB. Cervical cancer incidence in young US females after human papillomavirus vaccine introduction. Am J Prev Med. 2018;55(2):197-204. doi:10.1016/j.amepre.2018.03.013 - DOI - PMC - PubMed
    1. Mix JM, Van Dyne EA, Saraiya M, Hallowell BD, Thomas CC. Assessing impact of HPV vaccination on cervical cancer incidence among women aged 15-29 years in the United States, 1999-2017: an ecologic study. Cancer Epidemiol Biomarkers Prev. 2021;30(1):30-37. doi:10.1158/1055-9965.EPI-20-0846 - DOI - PMC - PubMed
    1. FUTURE II Study Group . Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions. N Engl J Med. 2007;356(19):1915-1927. doi:10.1056/NEJMoa061741 - DOI - PubMed
    1. Lei J, Ploner A, Elfström KM, et al. . HPV vaccination and the risk of invasive cervical cancer. N Engl J Med. 2020;383(14):1340-1348. doi:10.1056/NEJMoa1917338 - DOI - PubMed
    1. Watson M, Benard V, Flagg EW. Assessment of trends in cervical cancer screening rates using healthcare claims data: United States, 2003-2014. Prev Med Rep. 2018;9:124-130. doi:10.1016/j.pmedr.2018.01.010 - DOI - PMC - PubMed

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