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. 2022 Feb;84(2):e27-e29.
doi: 10.1016/j.jinf.2021.11.017. Epub 2021 Nov 27.

Serum calprotectin is not an independent predictor of severe COVID-19 in ambulatory adult patients

Alexander J Mentzer  1 , Tim James  2 , Mirak Yongya  2 , Stuart Cox  2 , Kevin Paddon  2 , Brian Shine  2 , Jordan Bowen  3 , Alex Novak  4 , Julian C Knight  5 , James N Fullerton  6
Affiliations

Serum calprotectin is not an independent predictor of severe COVID-19 in ambulatory adult patients

Alexander J Mentzer et al. J Infect. 2022 Feb.
No abstract available

Keywords: Biomarkers; COVID-19; Calprotectin; Emergency medicine; Viral infection.

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Conflict of interest statement

Declaration of Competing Interest Reagents for serum calprotectin measures were provided by Gentian AS. Gentian AS had no role in the design, performance or analysis of the study but reviewed the results and interpretation before presentation. All authors declare no conflicts of interest.

Figures

Fig 1
Fig. 1
Biomarkers to predict the risk of deterioration of patients presenting to ambulatory care with COVID-19. A) The receiver operating curve (ROC) distributions for three biomarkers associated with deterioration measured in 222 individuals with confirmed COVID-19. ROC analyses were undertaken using the pROC package and the comparison of the paired ROC statistics was calculated using DeLong's test. B) The Spearman rank rho correlation between the log10-transformed distributions of the predominant biomarkers associated with disease severity and deterioration in COVID-19 studies to date as measured in 771 individuals presenting to ambulatory care with symptoms consistent with COVID-19.
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