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. 2022 Jan;23(1):39.
doi: 10.3892/etm.2021.10961. Epub 2021 Nov 11.

Isolated liver trauma: A clinical perspective in a non-emergency center for liver surgery

Stefan Andrei  1   2 , Sebastian Isac  1   3 , Maricica Carstea  1 , Cristina Martac  1 , Lucian Mihalcea  1 , Cristina Buzatu  1 , Dorin Ionescu  4   5 , Dragos Eugen Georgescu  6 , Gabriela Droc  1   2
Affiliations

Isolated liver trauma: A clinical perspective in a non-emergency center for liver surgery

Stefan Andrei et al. Exp Ther Med. 2022 Jan.

Abstract

The management of liver trauma is, currently, still heterogeneous ranging from conservative to major invasive liver resections. When appropriate, these cases should be referred to a regional care center. The objective of this study was to analyze the expertise of a non-emergency center for liver surgery from Romania after initial stabilization in county hospitals. This study is a monocentric, retrospective, observational study, including 12 patients with hepatic trauma after a car accident, admitted between 2015 and 2019. We analyzed various clinical and biochemical data as independent variables, and the main outcome was considered the intensive care unit (ICU) length of stay. Our results revealed that intubation status at admission, norepinephrine infusion during surgery, hyperfibrinogenemia and duration of mechanical ventilation in patients with isolated liver trauma were correlated with prolonged ICU length of stay. Further prospective, more comprehensive studies are needed in order to evaluate the exact prognostic factors in terms of short- and long-term mortality.

Keywords: ICU stay; hyperfibrinogenemia; liver trauma; mechanical ventilation; norepinephrine.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
(A) The median ICU stay in patients with and without NE during surgery. The length of stay is expressed in days and the bars represents the median of the ICU stay. (B) The median ICU stay in non-intubated vs. intubated patients at admission. The length of stay is expressed in days and the bars represents the median of the ICU stay. ICU, intensive care unit; NE, norepinephrine.
See this image and copyright information in PMC

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