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The Sequence Read Archive (SRA, https://www.ncbi.nlm.nih.gov/sra/) stores raw sequencing data and alignment information to enhance reproducibility and facilitate new discoveries through data analysis. Here we note changes in storage designed to increase access and highlight analyses that augment metadata with taxonomic insight to help users select data. In addition, we present three unanticipated applications of taxonomic analysis.
Published by Oxford University Press on behalf of Nucleic Acids Research 2021.
Growth of SRA over the last decade. Through September 2021 Public Access contains…
Figure 1.
Growth of SRA over the last decade. Through September 2021 Public Access contains approximately 25.6 Petabase pairs originating from over 14.8 million publicly available runs averaging 1.7 Gbp per run, 0.83 GB per run, 9.6 million spots per run and 187 bp per spot.
Bonfield J.K., Mahoney M.V.. Compression of FASTQ and SAM format sequencing data. PLoS One. 2013; 8:e59190.
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Sayers E.W., Bolton E.E., Brister J.R., Canese K., Chan J., Comeau D.C., Connor R., Funk K., Chris C., Kim S.et al. .. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2021; 10.1093/nar/gkab1112.
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