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Case Reports
. 2022 Feb 1;205(3):357-359.
doi: 10.1164/rccm.202104-0826IM.

A Severe COVID-19 Pneumonia Revealing a Lepidic Adenocarcinoma: A Diagnostic Challenge during the Pandemic Period

Alexandre Elabbadi  1 , Anne Fajac  2 , Martine Antoine  2 , Jacques Cadranel  3 , Guillaume Voiriot  1 , Muriel Fartoukh  1 , Aude Gibelin  1
Affiliations
Case Reports

A Severe COVID-19 Pneumonia Revealing a Lepidic Adenocarcinoma: A Diagnostic Challenge during the Pandemic Period

Alexandre Elabbadi et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
(A) Computed tomography scan performed 5 months before ICU admission showing a left lower lobe consolidation (yellow arrow) with minimal peripheral ground-glass opacities (yellow dashed arrow); (B) computed tomography scan during ICU stay showing the extension of the left lower lobe consolidation (red arrow) and the appearance of bilateral ground-glass opacities (red dashed arrows).
Figure 2.
Figure 2.
BAL showing a majority of carcinoma cells. (A) May Grünwald Giemsa–stained cells from BAL after cytocentrifugation (×10). (B) Enlargement of A (×40). M = macrophages; T = tumor cell clusters.
Figure 3.
Figure 3.
Bronchial biopsy with nonmucinous adenocarcinomatous cells. (A) Hematoxylin and eosin safran staining (×20). (B) Expression of TTF1 (transcription termination factor 1) in the nuclei of the adenocarcinomatous cells exhibiting intense brown staining (×20). The asterisks indicate normal epithelial cells. G = bronchial glands; T = tumor cell.
See this image and copyright information in PMC

References

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