doi: 10.1126/science.3485310.
Molecular genetics of inherited variation in human color vision
- PMID: 3485310
- DOI: 10.1126/science.3485310
Item in Clipboard
Molecular genetics of inherited variation in human color vision
Science.
.
Abstract
The hypothesis that red-green "color blindness" is caused by alterations in the genes encoding red and green visual pigments has been tested and shown to be correct. Genomic DNA's from 25 males with various red-green color vision deficiencies were analyzed by Southern blot hybridization with the cloned red and green pigment genes as probes. The observed genotypes appear to result from unequal recombination or gene conversion (or both). Together with chromosome mapping experiments, these data identify each of the cloned human visual pigment genes.
Similar articles
-
The molecular basis of variation in human color vision.Clin Genet. 2005 May;67(5):369-77. doi: 10.1111/j.1399-0004.2004.00343.x. Clin Genet. 2005. PMID: 15811001 Review.
-
Color vision defects with variation in the exon 5 of red and green pigment genes.Yan Ke Xue Bao. 1998 Sep;14(3):130-3. Yan Ke Xue Bao. 1998. PMID: 12580020
-
The molecular basis of dichromatic color vision in males with multiple red and green visual pigment genes.Hum Mol Genet. 2002 Jan 1;11(1):23-32. doi: 10.1093/hmg/11.1.23. Hum Mol Genet. 2002. PMID: 11772996
-
Tandem array of human visual pigment genes at Xq28.Science. 1988 Jun 17;240(4859):1669-72. doi: 10.1126/science.2837827. Science. 1988. PMID: 2837827
-
Recent gene conversion between genes encoding human red and green visual pigments.Jpn J Genet. 1988 Aug;63(4):367-71. doi: 10.1266/jjg.63.367. Jpn J Genet. 1988. PMID: 3078877 Review.
Cited by
-
The evolution of rhodopsins and neurotransmitter receptors.J Mol Evol. 1991 Oct;33(4):367-78. doi: 10.1007/BF02102867. J Mol Evol. 1991. PMID: 1663559
-
Structures of human genes coding for cytokine LD78 and their expression.Mol Cell Biol. 1990 Jul;10(7):3646-58. doi: 10.1128/mcb.10.7.3646-3658.1990. Mol Cell Biol. 1990. PMID: 1694014 Free PMC article.
-
Molecular genetics of retinitis pigmentosa.West J Med. 1991 Oct;155(4):388-99. West J Med. 1991. PMID: 1771877 Free PMC article. Review.
-
Molecular genetics of X chromosome-linked color vision among populations of African and Japanese ancestry: high frequency of a shortened red pigment gene among Afro-Americans.Proc Natl Acad Sci U S A. 1990 Sep;87(17):6512-6. doi: 10.1073/pnas.87.17.6512. Proc Natl Acad Sci U S A. 1990. PMID: 2395857 Free PMC article.
-
The molecular basis of human 3-methylcrotonyl-CoA carboxylase deficiency.J Clin Invest. 2001 Feb;107(4):495-504. doi: 10.1172/JCI11948. J Clin Invest. 2001. PMID: 11181649 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Molecular Biology Databases
