Diagnosis of Anastomotic Leak
- PMID: 34853560
- PMCID: PMC8610633
- DOI: 10.1055/s-0041-1735270
Diagnosis of Anastomotic Leak
Abstract
Anastomotic leaks after colorectal surgery is associated with increased morbidity and mortality. Understanding the impact of anastomotic leaks and their risk factors can help the surgeon avoid any modifiable pitfalls. The diagnosis of an anastomotic leak can be elusive but can be discerned by the patient's global clinical assessment, adjunctive laboratory data and radiological assessment. The use of inflammatory markers such as C-Reactive Protein and Procalcitonin have recently gained traction as harbingers for a leak. A CT scan and/or a water soluble contrast study can further elucidate the location and severity of a leak. Further intervention is then individualized on the spectrum of simple observation with resolution or surgical intervention.
Keywords: CT scan; anastomosis; complications; leak.
Thieme. All rights reserved.
Conflict of interest statement
Conflict of Interest None declared.
Figures






References
-
- Dietz U A, Debus E-S. Intestinal anastomoses prior to 1882; a legacy of ingenuity, persistence, and research form a foundation for modern gastrointestinal surgery. World J Surg. 2005;29(03):396–401. - PubMed
-
- Hardy K J. Bowel surgery: some 18th and 19th century experience. Aust N Z J Surg. 1988;58(04):335–338. - PubMed
-
- Lindgren R, Hallböök O, Rutegård J, Sjödahl R, Matthiessen P. What is the risk for a permanent stoma after low anterior resection of the rectum for cancer? A six-year follow-up of a multicenter trial. Dis Colon Rectum. 2011;54(01):41–47. - PubMed
-
- Mirnezami A, Mirnezami R, Chandrakumaran K, Sasapu K, Sagar P, Finan P. Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis. Ann Surg. 2011;253(05):890–899. - PubMed
-
- Nordholm-Carstensen A, Rolff H C, Krarup P-M. Differential impact of anastomotic leak in patients with stage IV colonic or rectal cancer: a nationwide cohort study. Dis Colon Rectum. 2017;60(05):497–507. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Research Materials