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Meta-Analysis
. 2022 Oct;19(6):1319-1328.
doi: 10.1111/iwj.13726. Epub 2021 Dec 2.

Negative pressure wound therapy compared with conventional wound dressings for closed incisions in orthopaedic trauma surgery: A meta-analysis

Weiwei Xie  1 , Lingyan Dai  2 , Yameng Qi  3 , Xixi Jiang  1
Affiliations
Meta-Analysis

Negative pressure wound therapy compared with conventional wound dressings for closed incisions in orthopaedic trauma surgery: A meta-analysis

Weiwei Xie et al. Int Wound J. 2022 Oct.

Retraction in

Abstract

We performed a meta-analysis to evaluate the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. A systematic literature search up to October 2021 was done and 12 studies included 3555 subjects with closed incisions in orthopaedic trauma surgery at the start of the study: 1833 of them were provided with negative pressure wound therapy and 1722 were conventional wound dressings. They were reporting relationships about the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. We calculated the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to assess the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery using the dichotomous and continuous methods with a random or fixed-effect model. Negative pressure wound therapy had significantly lower deep surgical site infection (OR, 0.65; 95% CI, 0.48-0.88, P = .005), superficial surgical site infection (OR, 0.23; 95% CI, 0.11-0.49, P = .31), and wound dehiscence (OR, 0.41; 95% CI, 0.21-0.80, P = .009) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. However, negative pressure wound therapy had no significant effect on the length of hospital stay (MD, 0.29; 95% CI, -2.00- 2.58, P = .80) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Negative pressure wound therapy had significantly lower deep surgical site infection, superficial surgical site infection, and wound dehiscence; however, negative pressure wound therapy had no beneficial effect on the length of hospital stay compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Further studies are required to validate these findings.

Keywords: closed incisions; conventional wound dressing; length of hospital stay; negative pressure wound therapy; orthopaedic trauma surgery.

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Conflict of interest statement

The authors declare no potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Schematic illustration of the study method
FIGURE 2
FIGURE 2
A forest plot of the deep surgical site infection in negative pressure wound therapy group compared with the conventional wound dressings group
FIGURE 3
FIGURE 3
A forest plot of the superficial surgical site infection in negative pressure wound therapy group compared with the conventional wound dressings group
FIGURE 4
FIGURE 4
A forest plot of the wound dehiscence in negative pressure wound therapy group compared with the conventional wound dressings group
FIGURE 5
FIGURE 5
A forest plot of the length of hospital stay in negative pressure wound therapy group compared with the conventional wound dressings group
See this image and copyright information in PMC

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