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doi: 10.1016/j.cell.2021.11.020.
Epub 2021 Dec 1.
How a broadly neutralizing antibody grapples with antigenic and conformational diversity in dengue virus
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- PMID: 34856127
- DOI: 10.1016/j.cell.2021.11.020
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How a broadly neutralizing antibody grapples with antigenic and conformational diversity in dengue virus
Cell.
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Free article
Abstract
In this issue of Cell, two studies apply powerful structural approaches to probe the modes of interaction between a broadly neutralizing antibody and a conserved epitope found on four dengue virus serotypes and Zika virus. These findings offer new insights into how a broadly neutralizing antibody surmounts antigenic and conformational variation.
Copyright © 2021 Elsevier Inc. All rights reserved.
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Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.Cell. 2021 Dec 9;184(25):6067-6080.e13. doi: 10.1016/j.cell.2021.11.009. Epub 2021 Nov 30. Cell. 2021. PMID: 34852238
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