Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2022 Apr:68:22-30.
doi: 10.1016/j.jcrc.2021.11.008. Epub 2021 Nov 30.

In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M Schluep  1 , H Endeman  2 , B Y Gravesteijn  3 , C Kuijs  4 , M J Blans  5 , B van den Bogaard  6 , A W M M Koopman Van Gemert  7 , C J Hukshorn  8 , B J M van der Meer  9 , A H M Knook  10 , T van Melsen  11 , R Peters  12 , K S Simons  13 , G Spijkers  14 , J W Vermeijden  15 , E-J Wils  16 , R J Stolker  3 , S E Hoeks  3
Affiliations
Free article
Multicenter Study

In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M Schluep et al. J Crit Care. 2022 Apr.
Free article

Abstract

Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.

Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA.

Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65-0.87) at 3 months and 0.81 (0.70-0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8-46.5) and mental component scale (MCS) of 43.5 (34.0-39.7) and at 12 months a PCS of 43.1 (34.6-52.3) and MCS 46.9 (38.5-54.5).

Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

Keywords: Health-related quality of life; In-hospital cardiac arrest; Patient-reported outcome measures; Psychological wellbeing.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest This study was funded by Departmental Funds of the Participating Hospitals. Licensing of the SF-12 software (€800) was funded by the ESA Air Liquide unrestricted research grant 2017, as well as printing and postage costs (approx. €300).

Publication types