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. 2021 Dec;26(48):2101030.
doi: 10.2807/1560-7917.ES.2021.26.48.2101030.

Initial assessment of the COVID-19 vaccination's impact on case numbers, hospitalisations and deaths in people aged 80 years and older, 15 EU/EEA countries, December 2020 to May 2021

Nathalie Nicolay  1 , Francesco Innocenti  1   2 , Julien Beauté  1 , Veronika Učakar  3 , Marta Grgič Vitek  3 , Eero Poukka  4 , Tuula Hannila-Handelberg  4 , Charmaine Gauci  5 , Tanya Melillo  5 , Theano Georgakopoulou  6 , Jiri Jarkovsky  7 , Pavel Slezak  8 , Concepción Delgado-Sanz  9 , Carmen Olmedo-Lucerón  10 , Heleene Suija  11 , Rasa Liausediene  12 , Piaras O'Lorcain  13 , Niamh Murphy  13 , André Peralta-Santos  14 , Pedro Casaca  14 , Ioanna Gregoriou  15 , Nick Bundle  1 , Gianfranco Spiteri  1 , Giovanni Ravasi  1
Affiliations

Initial assessment of the COVID-19 vaccination's impact on case numbers, hospitalisations and deaths in people aged 80 years and older, 15 EU/EEA countries, December 2020 to May 2021

Nathalie Nicolay et al. Euro Surveill. 2021 Dec.

Abstract

Prioritisation of elderly people in COVID-19 vaccination campaigns aimed at reducing severe outcomes in this group. Using EU/EEA surveillance and vaccination uptake, we estimated the risk ratio of case, hospitalisation and death notifications in people 80 years and older compared with 25-59-year-olds. Highest impact was observed for full vaccination uptake 80% or higher with reductions in notification rates of cases up to 65% (IRR: 0.35; 95% CI: 0.13-0.99), hospitalisations up to 78% (IRR: 0.22; 95% CI: 0.13-0.37) and deaths up to 84% (IRR: 0.16; 95% CI: 0.13-0.20).

Keywords: COVID-19; health impact assessment; mass vaccination; vaccination uptake.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Incidence rate for case notifications in those 80 years and older, incidence rate ratio in those 80 years and older versus in 25–59-year-olds, and vaccine uptake of at least one dose or full vaccination in those 80 years and older by country, 15 EU/EEA countries, week 48 2020−week 20 2021
Figure 2
Figure 2
Adjusted incidence rate ratios for those 80 years and older versus 25–59-year-olds for case, hospitalisation and death notification rates, 15 EU/EEA countriesa, week 48 2020−week 20 2021
Figure 3
Figure 3
Incidence rate for hospitalisations in those 80 years and older, incidence rate ratio of hospitalisations in those 80 years and older versus 25–59-year-olds, and vaccine uptake of at least one dose or full vaccination in those 80 years and older by country, 15 EU/EEA countries, week 48 2020 to week 2 2021
Figure 4
Figure 4
Incidence rate for deaths in those 80 years and older, incidence rate ratio of deaths in those 80 years and older versus 25–59-year-olds, and vaccine uptake of at least one dose or full vaccination in those 80 years and older by country, 15 EU/EEA countries; week 48 2020 to week 20 2021
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References

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    1. European Centre for Disease Prevention Control (ECDC). Overview of the implementation of COVID-19 vaccination strategies and vaccine deployment plans in the EU/EEA: 6 May 2021. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/covid-19-overvi...
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