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Case Reports
. 2021 Nov 26:14:4977-4981.
doi: 10.2147/IDR.S342336. eCollection 2021.

Cutaneous Mycobacterium chelonae in a Patient with Sjogren's Syndrome

Lu Guo  1 , Sha Lv  1 , Jing Zeng  1 , Jiayu Yang  2 , Baihui Shan  1 , Fuqiu Li  1
Affiliations
Case Reports

Cutaneous Mycobacterium chelonae in a Patient with Sjogren's Syndrome

Lu Guo et al. Infect Drug Resist. .

Abstract

A case of cutaneous Mycobacterium chelonae infection in a patient with Sjogren's syndrome (SS) was misdiagnosed as sporotrichosis. A 56-year-old female patient was admitted to another hospital. Based on results of the histopathological examination and secretion culture obtained at the other hospital, the patient was diagnosed with sporotrichosis and received antifungal therapy. After treatment failure, the patient was admitted to our hospital, and a histopathological examination and secretion culture were performed again. The secretion culture revealed the presence of Mycobacterium chelonae. The antinuclear antibody test suggested SS, and the patient was treated with antibiotics and corticosteroids.

Keywords: Mycobacterium chelonae; cutaneous infection.

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Conflict of interest statement

The authors declare no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Swelling and purulent exudation from the wrist (A) to the left forearm (B); beaded proliferative nodules from the dorsum of the right hand (C) to the right forearm (D).
Figure 2
Figure 2
Scattered nodules on both knees (A) and the left lower limb (B).
Figure 3
Figure 3
The histopathological results showed superficial and deep granulomatous dermatitis with suppuration, multinucleated giant cells (A); negative periodic acid Schiff (PAS) staining (B); acid-fast bacilli were seen on skin biopsy stained with Ziehl–Neelsen stain (C).
Figure 4
Figure 4
White, smooth colonies was observed in potato dextrose agar (PDA) medium after 1 week.
Figure 5
Figure 5
Acid-fast staining of the bacterial suspension demonstrated acid-fast bacilli.
See this image and copyright information in PMC

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References

    1. Wallace RJ Jr, Brown BA, Onyi GO, et al. Skin, soft tissue, and bone infections due to Mycobacterium chelonae chelonae: importance of prior corticosteroid therapy, frequency of disseminated infections, and resistance to oral antimicrobials other than clarithromycin. J Infect Dis. 1992;166:405–412. doi:10.1093/infdis/166.2.405 - DOI - PubMed
    1. Lin SS, Lee CC, Jang TN. Soft tissue infection caused by rapid growing mycobacterium following medical procedures: two case reports and literature review. Ann Dermatol. 2014;26:236–240. doi:10.5021/ad.2014.26.2.236 - DOI - PMC - PubMed
    1. Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416. doi:10.1164/rccm.200604-571ST - DOI - PubMed
    1. Bhattacharya J, Mohandas S, Goldman DL, et al. Nontuberculous mycobacterial infections in children. Pediatr Rev. 2019;40:179–190. doi:10.1542/pir.2018-0131 - DOI - PubMed
    1. Brown-Elliott BA, Philley JV, Schlossberg D. Rapidly growing mycobacteria. Microbiol Spectr. 2017;5(1). doi:10.1128/microbiolspec.TNMI7-0027-2016 - DOI - PMC - PubMed

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