Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Nov 10:9:755484.
doi: 10.3389/fped.2021.755484. eCollection 2021.

Barriers and Proposed Solutions to a Successful Implementation of Pediatric Sepsis Protocols

Affiliations
Review

Barriers and Proposed Solutions to a Successful Implementation of Pediatric Sepsis Protocols

Daniela Nasu Monteiro Medeiros et al. Front Pediatr. .

Abstract

The implementation of managed protocols contributes to a systematized approach to the patient and continuous evaluation of results, focusing on improving clinical practice, early diagnosis, treatment, and outcomes. Advantages to the adoption of a pediatric sepsis recognition and treatment protocol include: a reduction in time to start fluid and antibiotic administration, decreased kidney dysfunction and organ dysfunction, reduction in length of stay, and even a decrease on mortality. Barriers are: absence of a written protocol, parental knowledge, early diagnosis by healthcare professionals, venous access, availability of antimicrobials and vasoactive drugs, conditions of work, engagement of healthcare professionals. There are challenges in low-middle-income countries (LMIC). The causes of sepsis and resources differ from high-income countries. Viral agent such as dengue, malaria are common in LMIC and initial approach differ from bacterial infections. Some authors found increased or no impact in mortality or increased length of stay associated with the implementation of the SCC sepsis bundle which reinforces the importance of adapting it to most frequent diseases, disposable resources, and characteristics of healthcare professionals. Conclusions: (1) be simple; (2) be precise; (3) education; (5) improve communication; (5) work as a team; (6) share and celebrate results.

Keywords: barriers; children; implementation; mortality; outcomes; protocol and guidelines.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. de Souza DC, Machado FR. Epidemiology of pediatric septic shock. J Pediatr Intensive Care. (2019) 8:3. 10.1055/s-0038-1676634 - DOI - PMC - PubMed
    1. Fernandez-Sarmiento J, Carcillo JA, Salinas CM, Galvis EF, Lopez PA, Jagua-Gualdron A. Effect of a sepsis educational intervention on hospital stay. Pediatr Crit Care Med. (2018) 19:e321 10.1097/PCC.0000000000001536 - DOI - PubMed
    1. Han YY, Carcillo JA, Dragotta MA, Bills DM, Watson RS, Westerman ME, et al. . Early reversal of pediatric-neonatal septic shock by community physicians is associated with improved outcome. Pediatrics. (2003) 112:793–9. 10.1542/peds.112.4.793 - DOI - PubMed
    1. Inwald DP, Tasker RC, Peters MJ, Nadel S. Emergency management of children with severe sepsis in the United Kingdom: the results of the Paediatric Intensive Care Society sepsis audit. Arch Dis Child. (2009) 94:348. 10.1136/adc.2008.153064 - DOI - PubMed
    1. National Academy of Sciences . Institute of Medicine Committee to Advise the Public Health Service. In: Field MJ, Lohr KN. editors. Clinical Practice Guidelines: Directions for a New Program. Washington, DC: National Academies Press; (1990). p. 36–8. - PubMed