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Case Reports
. 2022 Jun;104(6):e161-e163.
doi: 10.1308/rcsann.2021.0237. Epub 2021 Dec 3.

Peritoneal mesothelioma presenting with 'kissing' liver metastases

Affiliations
Case Reports

Peritoneal mesothelioma presenting with 'kissing' liver metastases

C Shaw et al. Ann R Coll Surg Engl. 2022 Jun.

Abstract

A 61-year-old woman was diagnosed with an incidental liver lesion with a satellite lesion that had features of a secondary liver metastasis. Investigations for primary sites did not reveal a primary tumour. The lesion was not amenable to biopsy due to location. Intraoperatively, the two lesions were adjacent, but the first was on the diaphragm and the lesion was in segment 7 of the liver. The liver lesion underwent non-anatomical resection and the diaphragmatic lesion was resected separately. The histopathology diagnosed peritoneal mesothelioma in the lesion removed from diaphragm and the liver lesion to be local metastatic spread to an area of liver that was in close contact (a 'kissing' lesion). This report portrays a rare occurrence of liver metastases from peritoneal mesothelioma and discusses the current evidence for diagnosis and treatment.

Keywords: Liver; Mesotheliomas; Metastases; Peritoneal.

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Figures

Figure 1
Figure 1
(a) Magnetic resonance imaging of the liver showing segment 7 lesions. (b) Positive emission tomography–computed tomography scan showing segment 7 lesions.
Figure 2
Figure 2
Histopathology staining positive for (a) CK5 and (b) calretinin.

References

    1. Boffetta P. Epidemiology of peritoneal mesothelioma: a review. Ann Oncol 2007; 18: 985–990. - PubMed
    1. Kumar V, Abbas A, Fausto N, Aster J. Robbins and Cotran Pathologic Basis of Disease. 8th edn. Philadelphia: Saunders Elsevier; 2010.
    1. García-Fadrique A, Mehta A, Mohamed F, et al. . Clinical presentation, diagnosis, classification and management of peritoneal mesothelioma: a review. J Gastrointest Oncol 2017; 8: 915–924. - PMC - PubMed
    1. Su SS, Zheng GQ, Liu YG, et al. . Malignant peritoneum mesothelioma with hepatic involvement: A single institution experience in 5 patients and review of the literature. Gastroenterol Res Pract 2016; 2016: 6242149. - PMC - PubMed

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