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. 2022 Feb;42(2):443-453.
doi: 10.1007/s10792-021-02061-z. Epub 2021 Dec 3.

Outcomes of surgical bleb revision at a tertiary Singapore eye hospital

Annabel C Y Chew  1   2   3   4 , Hla Myint Htoon  2   4 , Shamira A Perera  1   2   3   4 , Carlo J S Rubio  5 , Ching Lin Ho  6   7   8   9
Affiliations

Outcomes of surgical bleb revision at a tertiary Singapore eye hospital

Annabel C Y Chew et al. Int Ophthalmol. 2022 Feb.

Erratum in

Abstract

Purpose: To describe the outcomes of surgical bleb revisions from a tertiary glaucoma service in Singapore.

Methods: One hundred and thirty-one eyes of 129 patients who underwent surgical bleb revisions at the Singapore National Eye Centre between 2007 and 2014 were included in the study. The indications for bleb revision were: bleb-related infection (BRI), early and late bleb leak, early and late overfiltration, and bleb dysesthesia. Regression analysis was applied to elucidate risk factors.

Results: The mean age of the patients was 66 years, 62.6% were male, and 88.5% were Chinese. The majority of the eyes had primary glaucoma (79.4%). The mean interval from the initial trabeculectomy or phaco-trabeculectomy to the bleb revision was 58.8 months. The overall success rate was 69.5%. By Kaplan-Meier survival analysis, the overall cumulative success range fell from 78.6% to 49.1% over 10 years. Eyes with early bleb leak had lower surgical success compared to eyes with late bleb leak, early overfiltration and late overfiltration (P = 0.026, log-rank test). The IOP improved significantly post-operatively for eyes with BRI, early bleb leak, late bleb leak, early overfiltration and overfiltration (P < 0.05). Vision improved significantly in eyes with early overfiltration, but deteriorated in eyes with BRI (P < 0.05).

Conclusion: The overall success rate for surgical bleb revisions was good with complete resolution of the primary problem in the majority of cases. However, eyes with early bleb leak were less likely to have successful outcomes and should be monitored more closely post-operatively.

Keywords: Bleb revision; Glaucoma; Glaucoma surgery; Trabeculectomy complications.

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References

    1. Leung DY, Tham CC (2013) Management of bleb complications after trabeculectomy. Semin Ophthalmol 28(3):144–156 - DOI
    1. Gedde SJ, Herndon LW, Brandt JD et al (2012) Postoperative complications in the tube versus trabeculectomy (TVT) study during five years of follow-up. Am J Ophthalmol 153(5):804–814 - DOI
    1. La Borwit SE, Quigley HA, Jampel HD (2000) Bleb reduction and bleb repair after trabeculectomy. Ophthalmology 107:712–718 - DOI
    1. Bitrian E, Song B, Caprioli J (2014) Bleb revision for resolution of hypotony maculopathy following primary trabeculectomy. Am J Ophthalmol 158:597–604 - DOI
    1. Burnstein A, WuDunn D, Knotts S et al (2002) Conjunctival advancement versus nonincisional treatment for late-onset glaucoma filtering bleb leaks. Ophthalmology 109:71–75 - DOI

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