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Clinical Trial
. 2022 Feb 1;97(2):E75-E78.
doi: 10.1002/ajh.26429. Epub 2021 Dec 10.

Italian patients with hemoglobinopathies exhibit a 5-fold increase in age-standardized lethality due to SARS-CoV-2 infection

Filomena Longo  1 , Barbara Gianesin  2 , Vincenzo Voi  1 , Irene Motta  3   4 , Valeria Maria Pinto  5 , Andrea Piolatto  1 , Anna Spasiano  6 , Giovan Battista Ruffo  7 , Maria Rita Gamberini  8 , Susanna Barella  9 , Raffaella Mariani  10 , Carmelo Fidone  11 , Rosamaria Rosso  12 , Maddalena Casale  13 , Domenico Roberti  13 , Chiara Dal Zotto  14 , Angelantonio Vitucci  15 , Federico Bonetti  16 , Lorella Pitrolo  17 , Micol Quaresima  18 , Michela Ribersani  19 , Alessandra Quota  20 , Francesco Arcioni  21 , Saveria Campisi  22 , Antonella Massa  23 , Elisa De Michele  24 , Roberto Lisi  25 , Maurizio Miano  26 , Sabrina Bagnato  27 , Massimo Gentile  28 , Valentina Carrai  29 , Maria Caterina Putti  30 , Marilena Serra  31 , Carmen Gaglioti  1 , Margerita Migone De Amicis  4 , Giovanna Graziadei  4 , Anna De Giovanni  4 , Paolo Ricchi  6 , Manuela Balocco  5 , Sabrina Quintino  5 , Zelia Borsellino  7 , Monica Fortini  8 , Anna Rita Denotti  9 , Immacolata Tartaglione  13 , Andrea Beccaria  26 , Marco Marziali  19 , Aurelio Maggio  17 , Silverio Perrotta  13 , Alberto Piperno  10 , Aldo Filosa  6 , Maria Domenica Cappellini  4 , Lucia De Franceschi  14 , Antonio Piga  32 , Gian Luca Forni  5
Affiliations
Clinical Trial

Italian patients with hemoglobinopathies exhibit a 5-fold increase in age-standardized lethality due to SARS-CoV-2 infection

Filomena Longo et al. Am J Hematol. .
No abstract available

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Conflict of interest statement

No conflict of interest to declare.

Figures

FIGURE 1
FIGURE 1
(A) Characteristics of patients with hemoglobinopathies with SARS‐CoV‐2. (B) The population histogram shows age distribution of total population (gray), age distribution of SARS‐CoV‐2 infected (blue), and lethality rate at each class (red) for Italian general population* (left) and for Italian patients with hemoglobinopathies (right). (C) The table reports pre‐existing complications significantly associated with increased severity of COVID‐19, that is, hospital admission, intensive care unit (ICU) admission, or death. Odds ratio (OR) was estimated for single comorbidity by a logistic regression analysis adjusted for age to investigate possible factors related to different risk levels. *https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino‐sorveglianza‐integrata‐COVID‐19_10‐marzo‐2021.pdf
See this image and copyright information in PMC

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