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. 2021 Dec 2;28(12):2044-2046.
doi: 10.1016/j.stem.2021.11.008.

Stem cell-based islet replacement therapy in diabetes: A road trip that reached the clinic

Eelco J P de Koning  1 , Françoise Carlotti  2
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Stem cell-based islet replacement therapy in diabetes: A road trip that reached the clinic

Eelco J P de Koning et al. Cell Stem Cell. .
Free article

Abstract

One hundred years after the discovery of insulin, Kieffer and colleagues (Ramzy et al., 2021) and Foyt and colleagues (Shapiro et al., 2021) report interim results from a multicenter clinical trial showing insulin secretion from engrafted pluripotent stem cell-derived endocrine progenitor cells in patients with type 1 diabetes.

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Conflict of interest statement

Declaration of interests E.J.P.d.K. is councillor of the International Pancreas and Islet Transplantation Association and immediate past president of the European Pancreas and Islet Transplantation Association. E.J.P.d.K. has served as a consultant to Evotec.

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