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Case Reports
. 2022 Feb 1;41(2):e54-e57.
doi: 10.1097/INF.0000000000003418.

Successful Treatment of a Balamuthia mandrillaris Cerebral Abscess in a Pediatric Patient With Complete Surgical Resection and Antimicrobial Therapy

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Case Reports

Successful Treatment of a Balamuthia mandrillaris Cerebral Abscess in a Pediatric Patient With Complete Surgical Resection and Antimicrobial Therapy

Joshua A Cuoco et al. Pediatr Infect Dis J. .

Abstract

Cerebral amebic encephalitis due to Balamuthia mandrillaris is a rare yet typically fatal disease. As such, identification of the clinical characteristics, appropriate diagnostic workup and commencement of treatment is frequently delayed. Here, we present a case of a 4-year-old male with a B. mandrillaris cerebral abscess successfully treated with expedited neurosurgical resection and broad-spectrum antimicrobial therapy.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

References

    1. Qvarnstrom Y, Visvesvara GS, Sriram R, et al. Multiplex real-time PCR assay for simultaneous detection of Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri. J Clin Microbiol. 2006;44:3589–3595.
    1. Deetz TR, Sawyer MH, Billman G, et al. Successful treatment of Balamuthia amoebic encephalitis: presentation of 2 cases. Clin Infect Dis. 2003;37:1304–1312.
    1. Jung S, Schelper RL, Visvesvara GS, et al. Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome. Arch Pathol Lab Med. 2004;128:466–468.
    1. Schuster FL, Yagi S, Gavali S, et al. Under the radar: balamuthia amebic encephalitis. Clin Infect Dis. 2009;48:879–887.
    1. Martínez DY, Seas C, Bravo F, et al. Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement. Clin Infect Dis. 2010;51:e7–e11.

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