doi: 10.1042/bj2330929.
Binding of inositol trisphosphate by a liver microsomal fraction
- PMID: 3486656
- PMCID: PMC1153121
- DOI: 10.1042/bj2330929
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Binding of inositol trisphosphate by a liver microsomal fraction
Biochem J.
.
Abstract
Accumulating evidence suggests that the increase in cytosolic Ca2+ induced by receptor agonists is mediated by inositol 1,4,5-trisphosphate, a product of phospholipase C-mediated breakdown of phosphatidylinositol 4,5-bisphosphate. The present study employs inositol tris[32P]phosphate to demonstrate a specific receptor binding site in a microsomal fraction of rat liver.
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