Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan-Mar;44(1):7-12.
doi: 10.1016/j.htct.2021.08.013. Epub 2021 Nov 29.

Effect of ABO blood groups on length of hospital stay according to age in Covid-19 patients

Vildan Gursoy  1 , Suna Avci  2
Affiliations

Effect of ABO blood groups on length of hospital stay according to age in Covid-19 patients

Vildan Gursoy et al. Hematol Transfus Cell Ther. 2022 Jan-Mar.

Abstract

Introduction: Coronavirus Disease 2019 (COVID-19) is a novel viral disease with person-to-person transmission that has spread to many countries since the end of 2019. Although many unknowns were resolved within a year and the vaccine is available, it is still a major global health problem.

Objective: COVID-19 infection may present with a considerably wide spectrum of severity and host factors play a significant role in determining the course of the disease. One of these factors is blood groups. Based on previous experience, it is believed that the ABO blood group type affects prognosis, treatment response and length of stay in the hospital. In this study, our aim was to evaluate whether the blood group had an effect on the length of the hospital stay. To the best of our knowledge, no previous studies have assessed the effect of ABO blood groups, as well as age, on the length of the hospital stay in these settings.

Methods: In this retrospective cohort study, 969 patients admitted to our hospital between March 15, 2020 and May 15, 2020 were evaluated. The patients were divided into 4 groups according to ABO blood groups. The effect of the ABO blood group by age on the course of the disease, need for intensive care, duration of hospitalization and mortality in patients with COVID-19 infection, especially in geriatric patients, was evaluated.

Results: Of all the patients, 9.1% required admission to the intensive care unit (ICU), of whom 83% died. The average length of ICU stay was 11 days (0 - 59). The observed mortality rates in blood groups A, B, AB and 0 were 86.4%, 93.3%, 80.0% and 70.8%, respectively, indicating similar death rates in all ABO blood types. When the Rh phenotype was taken into consideration, no significant changes in results were seen.

Conclusion: As a result, we could not observe a significant relationship between blood groups and clinical outcomes in this study, which included a sample of Turkish patients with COVID-19.

Keywords: ABO blood groups; Coronavirus disease 2019; Geriatric patients; Length of hospital stay.

PubMed Disclaimer

Conflict of interest statement

All authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by

References

    1. Udwadia ZF, Tripathi AR, Nanda VJ, Joshi SR. Prognostic factors for adverse outcomes in COVID-19 infection. J Assoc Physicians India. 2020;68(7):62–66. Epub 2020/07/01. PubMed PMID: 32602683. - PubMed
    1. Anstee D. The relationship between blood groups and disease. Blood. 2010;115(23):4635–4643. - PubMed
    1. Cooling L. Blood groups in infection and host susceptibility. Clin Microbiol Rev. 2015;28(3):801–870. - PMC - PubMed
    1. Jing W, Zhao S, Liu J, Liu M. ABO blood groups and hepatitis B virus infection: a systematic review and meta-analysis. BMJ open. 2020;10(1) - PMC - PubMed
    1. Guillon P, Clément M, Sébille V, Rivain J-G, Chou C-F, Ruvoën-Clouet N, et al. Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies. Glycobiology. 2008;18(12):1085–1093. - PMC - PubMed