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Review
. 2021 Dec 6;13(1):14.
doi: 10.1186/s41479-021-00092-9.

Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

Anolin Aslan  1 , Cynthia Aslan  2   3 , Naime Majidi Zolbanin  4   5 , Reza Jafari  6   7
Affiliations
Review

Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

Anolin Aslan et al. Pneumonia (Nathan). .

Abstract

COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even though COVID-19 vaccinations are available now, there is still an urgent need to find potential treatments to ease the effects of COVID-19 on already sick patients. Multiple experimental drugs have been approved by the FDA with unknown efficacy and possible adverse effects. Probably the increasing number of studies worldwide examining the potential COVID-19 related therapies will help to identification of effective ARDS treatment. In this review article, we first provide a summary on immunopathology of ARDS next we will give an overview of management of patients with COVID-19 requiring intensive care unit (ICU), while focusing on the current treatment strategies being evaluated in the clinical trials in COVID-19-induced ARDS patients.

Keywords: ARDS; Acute respiratory distress syndrome; COVID-19; Pandemics; SARS-CoV-2.

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Conflict of interest statement

The authors declare that they have no conflict interests.

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