Bending toward differentiation
- PMID: 34875221
- DOI: 10.1016/j.devcel.2021.11.013
Bending toward differentiation
Abstract
Both biochemical and mechanical signals coordinate all processes at the origin of the formation of functional organs, including tissue folding, cell shape, and differentiation. In this issue of Developmental Cell, Blonski et al. establish a direct consequence of epithelial monolayer folding on nuclear shape and gene expression.
Copyright © 2021 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Direction of epithelial folding defines impact of mechanical forces on epithelial state.Dev Cell. 2021 Dec 6;56(23):3222-3234.e6. doi: 10.1016/j.devcel.2021.11.008. Dev Cell. 2021. PMID: 34875225
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