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. 2022 Mar:27:100284.
doi: 10.1016/j.jcte.2021.100284. Epub 2021 Dec 3.

COVID-19 and chronic fatigue syndrome: An endocrine perspective

Rashika Bansal  1 , Sriram Gubbi  1 , Christian A Koch  2   3
Affiliations

COVID-19 and chronic fatigue syndrome: An endocrine perspective

Rashika Bansal et al. J Clin Transl Endocrinol. 2022 Mar.

Abstract

Patients recovering from COVID-19 may have persistent debilitating symptoms requiring long term support through individually tailored cardiopulmonary and psychological rehabilitation programs. Clinicians need to be aware about the likely long-term complications and their diagnostic assessments to help identify any occult problems requiring additional help. Endocrinological evaluations should be considered as part of the armamentarium in the management of such individuals with diligent cognizance about the involvement of the hypothalamo-pituitary-adrenal (HPA) axis, adrenal and thyroid function. We here review the literature and potential pathophysiological mechanisms involved in and related to post COVID-19 symptoms with an emphasis on endocrine function.

Keywords: Adrenal function; COVID-19; Chronic Fatigue Syndrome; Endocrinopathy; Long Covid; Pain; Pituitary; Thyroid.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Potential pathophysiological mechanisms involved in the development of post-COVID syndrome and long COVID (Image courtesy: Sriram Gubbi, NIDDK, NIH).
Fig. 2
Fig. 2
Manifestations of long-COVID on the endocrine system (Image courtesy: Sriram Gubbi, NIDDK, NIH).
See this image and copyright information in PMC

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