Comparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae
- PMID: 3488021
- PMCID: PMC180505
- DOI: 10.1128/AAC.29.6.1090
Comparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae
Abstract
LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.
Similar articles
-
In vitro activity of cefdinir against respiratory pathogens isolated in Sicily with reference to beta-lactamase production.J Chemother. 1996 Jun;8(3):193-9. doi: 10.1179/joc.1996.8.3.193. J Chemother. 1996. PMID: 8808715
-
Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae?Antimicrob Agents Chemother. 2007 Sep;51(9):3463-4. doi: 10.1128/AAC.00190-07. Epub 2007 Jul 2. Antimicrob Agents Chemother. 2007. PMID: 17606681 Free PMC article. No abstract available.
-
Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a national multicenter surveillance study.Antimicrob Agents Chemother. 1997 Feb;41(2):292-7. doi: 10.1128/AAC.41.2.292. Antimicrob Agents Chemother. 1997. PMID: 9021182 Free PMC article.
-
Mechanisms of beta-lactam resistance in Haemophilus influenzae.Eur J Clin Microbiol Infect Dis. 1988 Oct;7(5):610-5. doi: 10.1007/BF01964237. Eur J Clin Microbiol Infect Dis. 1988. PMID: 3143572 Review.
-
Review of the spectrum and potency of orally administered cephalosporins and amoxicillin/clavulanate.Diagn Microbiol Infect Dis. 2007 Mar;57(3 Suppl):5S-12S. doi: 10.1016/j.diagmicrobio.2006.12.014. Epub 2007 Feb 9. Diagn Microbiol Infect Dis. 2007. PMID: 17292577 Review.
Cited by
-
beta-Lactamase stability and in vitro activity of oral cephalosporins against strains possessing well-characterized mechanisms of resistance.Antimicrob Agents Chemother. 1989 Aug;33(8):1313-7. doi: 10.1128/AAC.33.8.1313. Antimicrob Agents Chemother. 1989. PMID: 2802558 Free PMC article.
-
Amoxicillin/clavulanic acid. An update of its antibacterial activity, pharmacokinetic properties and therapeutic use.Drugs. 1990 Feb;39(2):264-307. doi: 10.2165/00003495-199039020-00008. Drugs. 1990. PMID: 2184003 Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical