Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Sep 16;11(4):221-224.
doi: 10.1055/s-0041-1734387. eCollection 2021 Oct.

An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria

Affiliations
Case Reports

An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria

Jaafer Zaino et al. Avicenna J Med. .

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome.

Keywords: arab; coronavirus disease 2019 (COVID-19); kawasaki disease; multisystem inflammatory syndrome in children (MIS-C); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
Erythematous macular rash.

Similar articles

References

    1. Dong Y, Mo X, Hu Y. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145(06):e20200702. - PubMed
    1. Centers for Disease Control and Prevention. Multisystem inflammatory syndrome in children (MIS-C) associated with Coronavirus disease. Available at: https://emergency.cdc.gov/han/2020/han00432.asp. Accessed September 23, 2020.
    1. Aronoff S C, Hall A, Del Vecchio M T. The natural history of SARS-Cov-2 related multisystem inflammatory syndrome in children (MIS-C): a systematic review. J Pediatr Infect Dis Soc. 2020;9(06):746–751. - PMC - PubMed
    1. American Academy of Pediatrics clinical guidance: multisystem inflammatory syndrome in children (MIS-C). Available at: https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infect.... Accessed June 9, 2021
    1. Overcoming COVID-19 Investigators; CDC COVID-19 Response Team . Feldstein L R, Rose E B, Horwitz S M. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med. 2020;383(04):334–346. - PMC - PubMed

Publication types