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Comparative Study
. 1986:31 Suppl 3:40-7.
doi: 10.2165/00003495-198600313-00011.

Classification of beta-lactamases from Branhamella catarrhalis in relation to penicillinases produced by other bacterial species

R Labia, M Barthelemy, C B Le Bouguennec, A Buu Hoi-Dang Van
Comparative Study

Classification of beta-lactamases from Branhamella catarrhalis in relation to penicillinases produced by other bacterial species

R Labia et al. Drugs. 1986.

Abstract

Branhamella catarrhalis strains resistant to commonly used penicillins, and presently isolated, produce a beta-lactamase. Most of these enzymes are chromosomally mediated, but a plasmid-mediated beta-lactamase has been described (enzyme BRO-1). With reference to isoelectric points, 7 different enzymes have been identified: 6 chromosomally mediated and 1 plasmid-mediated. Nevertheless, they have many common properties, such as being biosynthesised constitutively but with a low level of production. They have a penicillinase-type profile, and are strongly inhibited by clavulanic acid.

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