Interactomes in the era of deep learning

Joana Pereira^{1

2}, Torsten Schwede^{1

2}

Affiliations

¹ Biozentrum, University of Basel, Basel, Switzerland.
² SIB Swiss Institute of Bioinformatics, Biozentrum, University of Basel, Basel, Switzerland.

Comment

Joana Pereira et al. Science. 2021.

. 2021 Dec 10;374(6573):1319-1320.

doi: 10.1126/science.abm8295. Epub 2021 Dec 9.

Joana Pereira^{1

2}, Torsten Schwede^{1

2}

¹ Biozentrum, University of Basel, Basel, Switzerland.
² SIB Swiss Institute of Bioinformatics, Biozentrum, University of Basel, Basel, Switzerland.

Abstract

Deep learning provides an atomic snapshot of the yeast protein interactome.

Computed structures of core eukaryotic protein complexes.
Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D. Humphreys IR, et al. Science. 2021 Dec 10;374(6573):eabm4805. doi: 10.1126/science.abm4805. Epub 2021 Dec 10. Science. 2021. PMID: 34762488 Free PMC article.