Influenza A(H3N2) Outbreak on a University Campus - Michigan, October-November 2021
- PMID: 34882659
- PMCID: PMC8659183
- DOI: 10.15585/mmwr.mm7049e1
Influenza A(H3N2) Outbreak on a University Campus - Michigan, October-November 2021
Abstract
On November 10, 2021, the Michigan Department of Health and Human Services (MDHHS) was notified of a rapid increase in influenza A(H3N2) cases by the University Health Service (UHS) at the University of Michigan in Ann Arbor. Because this outbreak represented some of the first substantial influenza activity during the COVID-19 pandemic, CDC, in collaboration with the university, MDHHS, and local partners conducted an investigation to characterize and help control the outbreak. Beginning August 1, 2021, persons with COVID-19-like* or influenza-like illness evaluated at UHS received testing for SARS-CoV-2, influenza, and respiratory syncytial viruses by rapid multiplex molecular assay.† During October 6-November 19, a total of 745 laboratory-confirmed influenza cases were identified.§ Demographic information, genetic characterization of viruses, and influenza vaccination history data were reviewed. This activity was conducted consistent with applicable federal law and CDC policy.¶.
Conflict of interest statement
All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Emily T. Martin reports grants from Merck, outside the submitted work. Adam S. Lauring reports personal fees from Sanofi and personal fees from Roche, outside the submitted work. No other potential conflicts of interest were disclosed.
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References
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- Okoli GN, Racovitan F, Abdulwahid T, Righolt CH, Mahmud SM. Variable seasonal influenza vaccine effectiveness across geographical regions, age groups and levels of vaccine antigenic similarity with circulating virus strains: a systematic review and meta-analysis of the evidence from test-negative design studies after the 2009/10 influenza pandemic. Vaccine 2021;39:1225–40. 10.1016/j.vaccine.2021.01.032 - DOI - PubMed
-
- World Health Organization. Recommended composition of influenza virus vaccines for use in the 2021–2022 northern hemisphere influenza season. Wkly Epidemiol Rec 2021;96:77–88. https://cdn.who.int/media/docs/default-source/influenza/202102_recommend....
-
- World Health Organization. Recommended composition of influenza virus vaccines for use in the 2022 southern hemisphere influenza season. Wkly Epidemiol Rec 2021;96:509–20. https://cdn.who.int/media/docs/default-source/influenza/who-influenza-re....
-
- CDC. Health Alert Network: increasing seasonal influenza A (H3N2) activity, especially among young adults and in college and university settings, during SARS-CoV-2 co-circulation. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. https://emergency.cdc.gov/han/2021/han00458.asp
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